Vice President, US Brand Lead – Sigvotatug Vedotin

Pfizer

. Set the US brand vision and mobilize cross-functional operating model spanning Commercial, Medical, Market Access, Insights & Analytics, and Global partners .

Posted 5/7/2026full-timeNew York City • Illinois, Massachusetts, New York, Pennsylvania, Washington • 🇺🇸 United StatesSenior💰 $274,000 - $456,600 per yearWebsite

About the role

Key responsibilities & impact

Set the US brand vision and mobilize cross-functional operating model spanning Commercial, Medical, Market Access, Insights & Analytics, and Global partners
Own investment governance and outcomes, partnering closely with Finance and senior franchise leadership
Lead end-to-end US strategy from pre-launch through launch and into sustained performance
Build, lead, and inspire a high-performing US brand organization, establishing clear operating rhythms, talent development plans, succession pipelines, and an inclusive team culture
Own US P&L-aligned brand performance and all US pre-launch and launch activities, including strategic choices, investment governance, risk mitigation, and scenario planning in partnership with Finance and the franchise leadership team
Set the US go-to-market strategy and integrated launch plan, aligning with Global Brand Strategy, Market Access, Medical, and field leadership to deliver a cohesive, compliant customer experience
Provide executive leadership for the development of best-in-class HCP and patient strategy, positioning, and omnichannel content; ensure message architecture and evidence story are optimized through strong partnership with Global, Medical, and Regulatory
Identify, prioritize, and resource growth opportunities across indication expansion, segmentation, and lifecycle levers; translate insights into strategic choices with clear value cases and measurable outcomes
Lead development of annual and multi-year strategic and operating plans, integrating HCP, patient, access, and field execution strategies grounded in customer insights and competitive dynamics
Establish performance management and analytics governance for US marketing initiatives, driving actionable insights, continuous optimization, and clear readouts to senior leadership to improve decision velocity and ROI
Lead brand financial stewardship, including Annual Operating Plan, latest estimates, and investment allocation decisions; ensure resources are deployed to maximize patient impact and business results
Champion deep customer insight generation (field, medical, analytics, payers, and key opinion leaders) and translate insights into differentiated strategy, messaging, and executional choices
Own agency ecosystem strategy and governance (AOR and specialty partners) and manage a significant A&P budget with rigorous ROI discipline, compliant review processes, and a focus on creative effectiveness and speed-to-market

Requirements

What you’ll need

Bachelor’s degree required; advanced degree (MBA/PhD/MD) preferred
15+ years of progressive biopharma/healthcare experience, including significant US commercial leadership experience in specialty and/or oncology markets; 13+ years with MBA
Proven launch leader with end-to-end accountability for at least one major US product launch (pre-launch through post-launch performance), including omnichannel execution and field enablement
Demonstrated ability to lead through a complex matrix and partner at the executive level across Medical Affairs, Market Access, Field Leadership, Regulatory/Legal, Analytics, and Global teams
Strategic, enterprise mindset with demonstrated ability to make high-stakes trade-offs, build investment cases, and translate insights into clear choices and measurable outcomes
Executive presence with strong judgment, governance orientation, and the ability to escalate and resolve issues quickly while maintaining alignment across senior stakeholders
Exceptional communication and influencing skills—able to synthesize complexity into clear narratives for senior leadership and cross-functional teams
Significant people leadership experience, including leading leaders (e.g., Directors/Senior Directors) and building organizational capability through hiring, coaching, and succession planning
Demonstrated financial stewardship, including ownership of large budgets and experience with forecasting, performance management, and ROI-based investment decisions
Track record of delivering results in high-visibility, ambiguous environments with multiple priorities, strong compliance standards, and significant reputational and financial stakes.

Benefits

Comp & perks

Comprehensive and generous benefits and programs to help colleagues lead healthy lives
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits including medical, prescription drug, dental, and vision coverage

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

US brand strategyinvestment governanceP&L managementomnichannel executionfinancial stewardshipperformance managementanalytics governancestrategic planningrisk mitigationscenario planning

Soft Skills

leadershipcommunicationinfluencingstrategic thinkingjudgmentcollaborationproblem-solvingtalent developmentorganizational capabilitycustomer insight generation

Certifications

Bachelor's degreeMBAPhDMD