Senior Director, Transformation Engineering – Commercial AIA

Pfizer

. Reimagine Delivery by leading end-to-end rethinking of delivery and workflows, identifying where AI-native approaches can replace, augment, or eliminate existing processes .

Posted 5/6/2026full-timeNew York City • New York, Pennsylvania • 🇺🇸 United StatesSenior💰 $230,900 - $384,800 per yearWebsite

About the role

Key responsibilities & impact

Reimagine Delivery by leading end-to-end rethinking of delivery and workflows, identifying where AI-native approaches can replace, augment, or eliminate existing processes
Partner with senior leaders to surface high-impact transformation opportunities and translate them into actionable engineering roadmaps
Challenge legacy assumptions about how work gets done, and develop a clear point of view on what an AI-native operating model looks like
Define and execute the strategic technology approach for embedding AI agents, automation, and intelligent workflows into core operations
Set architectural direction for how applied engineering teams build, deploy, and scale AI-native products and tooling
Evaluate emerging AI capabilities and translate them into pragmatic, enterprise-grade solutions that deliver measurable outcomes
Shape how future applied engineers work — including team design, tooling, ways of working, and the human-agent collaboration model
Recruit, develop, and lead a high-performing team of engineers and technical leaders focused on transformation initiatives
Establish standards, frameworks, and best practices that scale AI-native engineering across the organization
Own outcomes for a portfolio of high-priority transformation initiatives, with clear KPIs tied to efficiency, quality, revenue, and experience
Communicate progress, tradeoffs, and recommendations to executive leadership and the board where appropriate
Build durable cross-functional partnerships with Product, Data, Commercial, and Operations leaders

Requirements

What you’ll need

12+ years of progressive experience in engineering, technology, or transformation leadership roles, including significant time leading senior technical teams
Bachelor’s Degree required
Demonstrated track record of leading large-scale transformation programs that delivered measurable business impact
Deep, current expertise in AI/ML, including hands-on understanding of agentic systems, LLM-based workflows, and AI-native product development
Strong systems thinking — able to move fluidly between operating model design, architecture, and execution
Executive-level communication skills, including the ability to influence senior business leaders and translate technical concepts into business outcomes
Experience building and leading high-performing engineering teams in a matrixed environment

Benefits

Comp & perks

401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
paid vacation
holiday and personal days
paid caregiver/parental and medical leave
health benefits to include medical, prescription drug, dental and vision coverage

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

AI/MLagentic systemsLLM-based workflowsAI-native product developmentsystems thinkingoperating model designarchitectureengineering roadmapsautomationintelligent workflows

Soft Skills

executive-level communicationinfluenceteam leadershipcross-functional collaborationstrategic thinkingproblem-solvingmentoringorganizational skillsadaptabilitystakeholder management

Certifications

Bachelor’s Degree