Clinical Pharmacology Lead

Pfizer

. Act as Clinical Pharmacology representative on Clinical Sub Team, Development Team and other multifunctional teams as appropriate .

Posted 5/5/2026full-timeCambridge • Connecticut, Massachusetts, New York • 🇺🇸 United StatesSenior💰 $106,000 - $176,600 per yearWebsite

About the role

Key responsibilities & impact

Act as Clinical Pharmacology representative on Clinical Sub Team, Development Team and other multifunctional teams as appropriate
Responsible for providing expertise, leadership, and deliverables of clinical pharmacology for the assigned projects within sphere of influence
With some guidance, design and execute clinical pharmacology plans and implement clinical pharmacology best practices on project teams
Work closely with other disciplines to ensure that sufficient preclinical PK/PD knowledge exists to underwrite safe human administration and to establish the structure of a predictive model prior to FIH
With some guidance, responsible for planning and overseeing clinical pharmacology aspects at the project level (e.g clinical development plan, implementation and interpretation of PK/PD analyses, PK/immunogenicity/biomarker measurement strategies etc.)
Plan and oversee study level activities including protocol authoring, clinical phase oversight, and reporting
With some guidance, responsible (with clinicians and statisticians) for ensuring appropriate dose-range finding strategies which ultimately will lead to optimal doses and dosage regimens in patients
Accountable for ensuring appropriate design and implementation of End-to-End MIDD plan that conforms with best practices
Responsible for ensuring use of innovative analytical methods to integrate knowledge of PK, PD, patient characteristics and disease states to optimize doses, dosage regimens and study designs
With some guidance, provide End-to-End clinical pharmacology contribution to regulatory documents (e.g., Briefing documents, Regulatory queries, Investigator’s Brochures, IND, NDA/MAA, etc.)
Stay abreast of literature, regulatory guidelines, and internal guidances and SOPs
Influence external environment through publications, presentations, and representation at scientific societies and industrial consortium.

Requirements

What you’ll need

Pharm. D., M.D./Ph.D., or equivalent training/experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or related discipline
Strong quantitative skills and expertise (e.g. experience in mechanistic PK/PD modeling/systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations using NONMEM, R, etc.)
0+ years of industry experience
Excellent written and verbal communication skills
Demonstrated presentation skills
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including the ability to influence and collaborate with peers to achieve meaningful outcomes and create business impact.

Benefits

Comp & perks

401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical pharmacologypharmacokineticspharmacometricsmechanistic PK/PD modelingpopulation modelingclinical trial simulationsdose-range finding strategiesanalytical methodsbiomarker measurement strategiesprotocol authoring

Soft Skills

leadershipcommunication skillspresentation skillscollaborationinfluenceorganizational skillsproblem-solvingcritical thinkingteamworkadaptability

Certifications

Pharm. D.M.D.Ph.D.