Senior Director, Clinical Pharmacology, Pharmacometrics
Parabilis Medicines
full-time
Posted on:
Location Type: Remote
Location: Massachusetts • United States
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Salary
💰 $250,000 - $300,000 per year
Job Level
About the role
- Provide scientific, functional, and operational leadership across assigned drug development programs.
- Design and execute program-level clinical pharmacology and pharmacometric strategies.
- Ensure integration into global development plans.
- Work cross-functionally with Clinical Development, DMPK, Regulatory, and Biostatistics to optimize dose selection.
- Oversee planning, conduct, and interpretation of clinical pharmacology studies.
- Author and review clinical pharmacology sections of regulatory submissions.
Requirements
- PhD, PharmD, MD, or equivalent in Clinical Pharmacology, Pharmaceutical Sciences, or a related quantitative discipline.
- 12+ years of experience in clinical pharmacology, pharmacometrics, or quantitative drug development in the biopharmaceutical industry.
- Demonstrated success in designing and leading clinical pharmacology strategies at the program or portfolio level.
- Strong understanding of regulatory expectations (FDA, EMA, PMDA, NMPA) for clinical pharmacology and modeling & simulation.
- Proficiency in modeling and data analysis tools (e.g., NONMEM, Monolix, Phoenix NLME, MATLAB, R).
- Proven ability to lead in matrixed environments, influence cross-functional teams, and drive decision-making.
- Experience with both small molecules and biologics; exposure to novel modalities (e.g., gene or cell therapies) preferred.
- Excellent communication, collaboration, and presentation skills.
- Demonstrated use of AI tools in your current role and responsibilities is required. Advanced or innovated use of AI is a strong plus.
Benefits
- Parabilis’s total compensation package includes an annual target bonus
- equity
- a comprehensive suite of competitive benefits designed to support our employees’ overall well-being
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
clinical pharmacologypharmacometricsquantitative drug developmentmodeling and simulationdata analysisdose selectionclinical pharmacology strategiesregulatory submissionssmall moleculesbiologics
Soft skills
leadershipcollaborationcommunicationpresentationinfluencedecision-making
Certifications
PhDPharmDMD