Outpace Bio

Translator

• Provide strategic, technical and scientific functional leadership and build productive relationships in matrix teams to advance fit-for-purpose translational strategies in support of Outpace’s innovative cell therapy programs.
• Design and deliver translational strategies including patient selection/stratification, pharmacokinetic, pharmacodynamic, mechanism of action, resistance and toxicity, prognostic and predictive biomarkers, and support indication expansion, and asset differentiation to support programs in all phases of development.
• Effectively manage and communicate key biomarker program information, risks, milestones, data and interpretation to asset teams and other stakeholders.
• Responsible for the preparation and review of biomarker sections of candidate nomination, IND package, Clinical Development Plan, clinical protocols, ICFs and regulatory documents.
• Act as Translational Sciences representative in relevant asset team and/or lead/contribute to translational subteams in collaboration with translational operations, clinical development, clinical operations, research, CMC, regulatory, quality, program management and business development.
• Productively engages with external collaborators and scientific KOLs to support translational goals.
• Contribute to the growth and excellence of the Translational Sciences team, execute continuous improvement initiatives to enhance quality, cost effectiveness, scalability, and long-term implementation of translational initiatives.
• Responsible for the engagement and management of outsourced Central and Specialty labs to generate high quality data, according to plan and established timelines.
• Design and implement fit-for-purpose outsourced qualification/validation for clinical biomarker assays to ensure high scientific quality of target expression, patient selection, PK, target engagement / pharmacodynamics, ATA, prognostic, predictive and safety biomarker data to support program decision-making.

Director, Translational Sciences

Director

Outpace Bio is pioneering the future of cell therapy for solid tumors by harnessing unrivaled AI-powered protein design. Our mission is to program immune cells for enhanced function inside patients, overcoming key barriers such as poor tumor access, weak survival, antigen escape, and dose-related toxicity.
To enable this vision we are seeking a highly motivated and experienced Director/Senior Director of Project & Portfolio Management to help lead our cross-functional teams designing and advancing programmed T cell therapies into the clinic. Reporting to the Chief Business Officer, you will play a pivotal role in managing drug development projects at both preclinical and clinical stages.
Partnering with Asset and Project Team Leaders, you will foster a high-performing team environment while driving the development and execution of integrated project plans across functional disciplines. As the central source of project status, you will ensure alignment, facilitate timely decision-making, and escalate challenges as needed.
In addition to managing individual projects, you will contribute to building project management tools and methodologies to support initiatives across our portfolio. This role may also involve serving as an alliance manager for external partners and vendors.

Director, Translational Sciences

Director/Senior Director, Project & Portfolio Management, PPM