Principal Analyst, Statistical Programming

Neurocrine Biosciences

Principal statistical programmer leading SAS clinical-data programming for Neurocrine Biosciences, a biopharmaceutical company. Guiding clinical-study reporting, CDISC standards, vendors, and regulatory submissions.

Posted 8/13/2026full-timeSan Diego • California • 🇺🇸 United StatesLead💰 $130,800 - $179,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates advanced expertise in SAS programming, including Base, Stat, Macro, and graph, along with a strong understanding of CDISC data structures and regulatory guidelines. Proven ability to lead multidisciplinary projects, manage teams, and ensure high-quality statistical programming deliverables in a clinical environment.

Highest-signal resume keywords

Advanced SAS Programming SkillsCDISC Data Structures KnowledgeProject Management ExperienceStatistical Programming LeadershipExpert Knowledge of ICH Guidelines

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

SAS ProgrammingStatistical ProgrammingCDISC ImplementationRelational DatabasesStatistical AnalysisProgramming Standards DevelopmentData ValidationStatistical Programming SOPsProject ManagementQuality Control

Soft Skills

Leadership SkillsAnalytical ThinkingProblem-Solving SkillsCommunication SkillsOrganizational Skills

Tools & Technologies

SASRWordExcelPowerPoint

Industry Keywords

BiopharmaceuticalCROICH Guidelines21 CFR Part 11FDA GuidelinesSDTM DomainsADaM Data SetsDefine.xml FilesClinical DataE-Submission Requirements

About the role

Key responsibilities & impact

Lead the design, development, testing, maintenance, validation, and documentation of SAS programs evaluating clinical data
Provide advanced technical statistical programming leadership within Biometrics
Serve as a technical resource for statistical programmers
Participate in hiring, training, and oversight of statistical programmers
Lead large, multidisciplinary projects and serve as the primary Statistical Programming point of contact
Direct development and implementation of programming standards, conventions, and infrastructure
Assess workload and projects to ensure programming resources are available
Oversee and validate vendor programming activities, including CDISC implementation and analysis reporting
Support creation and validation of e-submission requirements, including annotated CRFs, datasets, and define documents
Serve as primary or lead programmer for agency reporting deliverables such as DSUR/Annual Report and IB updates
Perform lead and/or quality control statistical programming on projects as needed
Perform other duties as assigned

Requirements

What you’ll need

BS/BA degree in computer science, mathematics, statistics, or related discipline and 6+ years of biopharmaceutical or CRO statistical programming experience; or Master’s degree and 4+ years; or PhD and 2+ years
At least three years of experience serving in a supervisory or lead capacity
Advanced knowledge of SAS, including Base, Stat, Macro, and graph
Advanced knowledge of CDISC data structures, SDTM domains, ADaM data sets, and Define.xml files
Experience managing large projects and external vendors
Knowledge of best practices in the functional discipline and related business disciplines
Advanced SAS programming skills and expertise developing and implementing statistical programming SOPs and processes in a clinical environment
Knowledge of writing, validating, and documenting statistical programs and creating integrated programming libraries and systems
Project management experience with minimum supervision
Ability to organize and manage multiple assignments with challenging timelines across multiple personnel
Advanced understanding of relational databases and complex data systems
Expert knowledge of ICH guidelines, CDISC data structures, 21 CFR Part 11, and FDA guidelines
Advanced programming skills in SAS, R, STAT, or similar
Proficiency with Word, Excel, and PowerPoint
Excellent computer, communication, problem-solving, analytical thinking, project management, and leadership skills
Ability to work as part of and lead multiple teams
Ability to meet multiple deadlines with high accuracy and efficiency

Benefits

Comp & perks

Annual bonus with a target of 30% of the earned base salary
Eligibility to participate in the equity based long term incentive program
Retirement savings plan with company match
Paid vacation
Paid holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage