Senior Bioinformatics Scientist

Natera

Senior Bioinformatics Scientist leading genomic pipeline development for Natera. Focused on building production-grade software tools for analyzing next-generation sequencing data.

Posted 6/24/2026full-timeRemote • California • 🇺🇸 United StatesSenior💰 $117,400 - $146,800 per yearWebsite

Tech Stack

Tools & technologies

AWSCloudLinuxMySQLNumpyPandasPythonScikit-Learn

About the role

Key responsibilities & impact

Analyze complex genomic datasets leveraging scaled in-house pipelines
Architect, build, and deploy automated analysis pipelines for diagnostic tests
Engineer novel genomic analysis tools and proactively identify optimization pathways
Participate in code reviews, technical documentation
Coordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systems

Requirements

What you’ll need

Ph.D. or Master's degree with a minimum of 5 years of professional experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field.
Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows.
Advanced understanding of data structures, algorithm design, and computational complexity.
Strong Python programming skills, including fluency with the scientific computing stack (NumPy, Pandas, Scikit-learn) for data manipulation, analysis, and automation.
Proficiency with workflow languages — Nextflow or WDL strongly preferred.
Extensive experience in distributed computing and cloud environments; AWS strongly preferred.
Deep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scripts.
Demonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challenges.
Excellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholders.
Prior experience working with relational databases, particularly MySQL, is highly desirable.

Benefits

Comp & perks

Comprehensive medical plans for eligible employees and their dependents
Dental plans for eligible employees and their dependents
Vision plans for eligible employees and their dependents
Life insurance and disability plans
Free testing for Natera employees and their immediate families
Fertility care benefits
Pregnancy and baby bonding leave
401k benefits
Commuter benefits
Generous employee referral program

ATS Keywords

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Hard Skills & Tools

bioinformaticshigh-throughput DNA sequence data analysismappingsequence alignmentvariant callingPythonNumPyPandasScikit-learnNextflow

Soft Skills

communicationtechnical autonomydata discipline

Certifications

Ph.D.Master's degree