Senior AI/ML Engineer

Natera

Senior AI/ML Engineer designing and deploying Natera’s Generative AI and Machine Learning platforms. Focusing on building compliant and efficient systems that improve patient outcomes.

Posted 6/17/2026full-timeRemote • Texas • 🇺🇸 United StatesSenior💰 $125,000 - $156,300 per yearWebsite

Tech Stack

Tools & technologies

AWSCloudPythonPyTorchSparkTensorflow

About the role

Key responsibilities & impact

Design, build, and deploy Natera’s Generative AI and Machine Learning platforms.
Develop a production-ready Generative AI and MLOps platform with reusable components.
Design and implement foundational GenAI services: vector search, prompt tuning, agent orchestration, document extraction, etc.
Build standardized APIs/SDKs for product teams to deploy and monitor Generative AI workloads.
Ensure platform components meet enterprise-grade requirements.
Implement RAG at scale: ingestion pipelines, chunking/embedding policies, and feedback loops.
Collaborate with research teams to prototype multi-agent architectures for workflow automation.
Optimize compute and storage architecture for cost-effective scaling of large models.

Requirements

What you’ll need

8+ years in software/ML engineering, with 5+ years in ML engineering at scale.
Expertise in building production-grade ML/LLM systems on AWS tech stack (Python, TensorFlow/PyTorch, Spark, MLflow/Kubeflow, vector DBs).
Proven track record with GenAI/LLMs: fine-tuning, RAG, prompt orchestration, agentic systems, safety guardrails, monitoring, and cost optimization.
Hands-on with RAG systems (embeddings, vector DBs, retrieval policies) and LLM runtime operations (caching, quotas, multi-model routing).
Experience building agentic AI platforms (LangChain, LlamaIndex, CrewAI, Semantic Kernel, or custom).
Deep knowledge of data-intensive systems, distributed architectures, and cloud-native development.
Strong grounding in compliance-first engineering in healthcare, biotech, or diagnostics preferred.
Track record building secure, compliant data/AI systems and automating policy checks.
Excellent ability to influence across teams, mentor engineers, and set technical standards.

Benefits

Comp & perks

Comprehensive medical, dental, vision, life, and disability plans for eligible employees and their dependents.
Free testing for Natera employees and their immediate families.
Fertility care benefits.
Pregnancy and baby bonding leave.
401k benefits.
Commuter benefits.
Generous employee referral program.

ATS Keywords

✓ Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools

Generative AIMachine LearningMLOpsPythonTensorFlowPyTorchSparkMLflowKubeflowvector databases

Soft Skills

influencementoringsetting technical standards