Senior Software Engineer, Voice AI

Natera

Senior Software Engineer developing voice AI architecture and overseeing the Voice AI platform at Natera. Focusing on healthcare solutions and production systems for patient interactions.

Posted 5/26/2026full-timeRemote • California • 🇺🇸 United StatesSeniorWebsite

Tech Stack

Tools & technologies

AzureJavaScriptNode.jsTypeScript

About the role

Key responsibilities & impact

Own the end-to-end voice AI architecture — from Twilio media streams through LLM orchestration to TTS output and call disposition.
Design and implement multi-agent systems using tool calling, agent handoffs, and shared conversation state for complex patient workflows.
Build and optimize real-time audio pipelines — WebSocket streaming, codec handling (mulaw/PCM), VAD configuration, and interruption management.
Architect analytics and observability infrastructure for voice-specific metrics: per-segment latency (STT/LLM/TTS), call efficacy, disposition accuracy, and ASR error rates.
Solve voice-specific challenges: turn-taking timing, silence detection thresholds, barge-in recovery, medical term recognition, and end-to-end latency optimization.
Integrate voice agents with internal services via secure authenticated APIs.
Drive platform reliability — eliminate single points of failure, implement multi-provider LLM failover, and design graceful degradation paths.
Collaborate with product and clinical operations to improve self-serve efficacy rates and reduce call escalations.
Mentor team members on voice AI best practices and contribute to architectural decisions.

Requirements

What you’ll need

5+ years of software engineering experience, with at least 2 years building production voice AI or conversational AI systems.
Deep experience with voice AI pipelines — understanding the end-to-end flow from telephony through STT, LLM processing, TTS, and back to the caller.
Production experience with agentic architectures — multi-agent orchestration, tool calling, agent handoffs, memory/state management.
Strong understanding of voice-specific challenges: VAD tuning, turn-taking, interruption/barge-in handling, latency budgets, audio codec management.
Hands-on experience with telephony systems — Twilio (media streams, SIP, IVR), or equivalent platforms with WebSocket-based audio streaming.
Proficiency in TypeScript/Node.js with strong async programming patterns; experience with NestJS or similar frameworks.
Experience with STT/TTS providers (Deepgram, OpenAI, ElevenLabs, Azure Speech).
Production experience with LLM APIs — OpenAI (especially Realtime API), Anthropic Claude, or equivalent; prompt engineering for conversational agents.
High agency and autonomy — you don't wait for permission or detailed specs.
Excellent communication skills to translate complex voice AI architecture decisions.

Benefits

Comp & perks

Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
Free testing for employees and their immediate families.
Fertility care benefits.
Pregnancy and baby bonding leave.
401k benefits.
Commuter benefits.
Employee referral program.

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

voice AI architecturemulti-agent systemsreal-time audio pipelinesWebSocket streamingcodec handlingVAD configurationanalytics infrastructureAPI integrationTypeScriptNode.js

Soft Skills

mentoringcollaborationcommunicationproblem-solvingautonomy