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Associate Director – Real-World Evidence, Observational Research
NateraAssociate Director of Real-World Evidence driving evidence initiatives for early cancer detection at Natera. Leading cross-functional research strategies and partnerships to inform product adoption and clinical use.
About the role
Key responsibilities & impact- Lead the design and execution of real-world evidence studies, including retrospective database analyses and prospective observational studies.
- Contribute to clinical evidence strategy for a defined product area, identifying where RWE can address key evidence gaps.
- Translate clinical, scientific, and business questions into robust, decision-oriented study designs.
- Proactively identify risks to study execution and implement mitigation strategies.
- Lead to protocol development, including objectives/endpoints, eligibility criteria, data collection approaches, and analysis plans.
- Partner with biostatistics and data science to ensure high-quality data analysis, interpretation, and reporting.
- Drive medical data review, interpretation, and synthesis of findings.
- Deliver clear, actionable insights that inform product strategy, clinical positioning, and market access.
- Evaluate real-world product performance and identify opportunities to improve adoption, utilization, and outcomes.
- Partner with Product and Medical Affairs to ensure real-world insights are fed back into product development.
- Contribute to evidence planning by identifying where RWE can most effectively address key gaps.
- Support prioritization of studies based on business impact, feasibility, and timing.
- Ensure alignment between RWE, clinical studies, and broader evidence generation efforts.
- Support development of publications, abstracts, and presentations to communicate evidence externally.
- Partner with Medical Affairs and Market Access to translate evidence into compelling narratives for clinicians, KOLs, and payers.
Requirements
What you’ll need- Advanced degree (PhD, MPH, MS, PharmD, or equivalent) in epidemiology, health outcomes research, biostatistics, or related field.
- 7–10+ years of experience in real-world evidence, observational research, or HEOR, ideally in industry.
- Demonstrated experience leading the design and execution of observational studies across the full lifecycle (protocol through analysis and dissemination).
- Strong understanding of real-world data sources (claims, EHR, registries) and their application to clinical and business questions.
Benefits
Comp & perks- Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
- Free testing for employees and their immediate families.
- Fertility care benefits.
- Pregnancy and baby bonding leave.
- 401k benefits.
- Commuter benefits.
- Employee referral program.
ATS Keywords
✓ Tailor your resumeApplicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
real-world evidenceobservational studiesprotocol developmentdata analysisdata interpretationrisk mitigation strategiesevidence planningclinical evidence strategybiostatisticshealth outcomes research
Soft Skills
leadershipcommunicationcollaborationproblem-solvingstrategic thinkinginsight deliveryprioritizationadaptabilitystakeholder engagementnarrative development
Certifications
PhDMPHMSPharmD