Natera

Lead Product Manager, Clinical Genomics

Natera

full-time

Posted on:

Location Type: Remote

Location: United States

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Salary

💰 $143,200 - $179,000 per year

Job Level

Senior

About the role

  • Define and drive multi-year product strategy and roadmap across one or more RIR components, ensuring alignment to clinical quality, regulatory requirements, and commercial scale objectives
  • Influence platform-level technical direction in partnership with engineering leadership
  • Partner closely with software engineering, bioinformatics, clinical domain experts, quality, regulatory, and other product teams
  • Translate business, clinical, and operational needs into clear, actionable product requirements
  • Define and evolve end-to-end user workflows, including UI/UX requirements and supporting backend functionality
  • Drive cross-team alignment on shared data contracts and workflow standards
  • Mentor and raise the bar for product management within the RIR organization
  • Own measurable improvements in clinical workflow efficiency, reliability, and operational scalability
  • Establish prioritization frameworks that balance regulatory risk, clinical impact, technical scalability, and business outcomes across RIR investments.
  • Develop and track quantitative metrics related to usability, performance, reliability, and adoption
  • Lead delivery teams with clear strategic direction, ensuring requirements reflect long-term platform goals, validation readiness, and system interoperability.
  • Proactively identify systemic risks, architectural constraints, and workflow inefficiencies that may limit scale or regulatory robustness, and lead cross-functional initiatives to resolve them
  • Partner with Quality and Regulatory leadership to shape validation strategy, risk classification, traceability, and audit readiness for RIR software systems.
  • Create clear, data-driven written proposals and presentations to support stakeholder alignment and decision-making
  • Act as a subject matter expert for owned components, supporting design, testing, validation, rollout, and ongoing use

Requirements

  • Bachelor’s degree in life sciences, engineering, computer science, statistics, or equivalent experience
  • 7+ years of experience in software product management, including ownership of complex, multi-team or platform-level initiatives
  • 5+ years experience working on production software in healthcare, clinical genomics, or other regulated lifesciences domains, with demonstrated impact on validation, compliance, and system scalability
  • Demonstrated experience influencing engineering architecture and long-term technical investment decisions
  • Proven ability to drive alignment across highly matrixed organizations without direct authority
  • Track record of independently operating in ambiguous environments and establishing product direction
Benefits
  • Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
  • Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
  • Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
  • We also offer a generous employee referral program!
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
product strategyproduct roadmapUI/UX designdata contractsquantitative metricssystem interoperabilityvalidation strategyrisk classificationaudit readinessworkflow efficiency
Soft Skills
influencementorshipcross-team alignmentstakeholder alignmentdecision-makingindependent operationambiguity managementstrategic directioncommunicationleadership