Natera

Principal AI Software Engineer – Enterprise AI Platform

Natera

full-time

Posted on:

Location Type: Remote

Location: Remote • 🇺🇸 United States

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Salary

💰 $174,400 - $218,000 per year

Job Level

Lead

Tech Stack

AirflowAWSCloudDistributed SystemsDockerKubernetesPython

About the role

  • The Enterprise AI Platform Engineer is responsible for build and delivery of Natera’s enterprise agentic AI platform.
  • You will architect and build the core AI operating system that powers modular, low-code enterprise AI agentic automation that is complete with agent templates, agent orchestration engine, data and MCP connectors, prompt optimization capabilities, evaluation guardrails, abstracted AI services, intelligent data extraction and reasoning capabilities.
  • Design and implement the core architecture of the Enterprise AI Platform — low code, modular, scalable, and secure.
  • Build the agent orchestration runtime, including task queues, state management, and inter-agent communication.
  • Architect for long-running, resilient AI workflows, enabling agents to execute and monitor multi-step, asynchronous processes.
  • Develop APIs and services for automation, evaluation, and agent lifecycle management.
  • Establish DevOps, CI/CD pipelines, and configuration management to ensure smooth deployment at scale.

Requirements

  • 12+ years of software engineering experience, with 8+ years in platform or distributed systems architecture.
  • Proven expertise in implementing workflow orchestration or automation systems
  • Proficiency in Python with deep experience in backend architecture and API design.
  • Experience with low-code/no-code automation platforms (Zapier, n8n etc.), internal developer platforms (IDPs), or workflow engines (Temporal, Airflow).
  • Experience in working with well known agentic cloud platforms (e.g. AWS Bedrock agents, AgentCore etc.).
  • Hands-on experience with LLMs, RAG, vector databases, and orchestration frameworks (LangChain, LlamaIndex, AutoGen, DSPy).
  • Fluency in cloud infrastructure, Kubernetes, Docker, and CI/CD automation.
  • Knowledge of observability and telemetry systems for event-driven environments.
  • Familiarity with AI governance and evaluation frameworks, LLM safety, drift detection, bias detection, hallucination, explainability, and compliance (e.g., HIPAA, CLIA, FDA).
Benefits
  • Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
  • Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
  • Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
  • We also offer a generous employee referral program!

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard skills
Pythonbackend architectureAPI designworkflow orchestrationautomation systemslow-code platformscloud platformsLLMsKubernetesDocker