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Principal Scientist, Clinical Research
MSDPrincipal Scientist leading early clinical development strategy for novel therapeutics in Translational Medicine. Collaborating with Discovery Sciences and late-stage Clinical Research teams to support drug development.
Posted 7/10/2026full-timeMassachusetts, New Jersey, Pennsylvania • 🇺🇸 United StatesMid-LevelSenior💰 $190,800 - $300,300 per yearWebsite
About the role
Key responsibilities & impact- Key member of an early development team, providing leadership in designing and executing early clinical development strategy
- Development and execution of early clinical strategy for novel therapeutics including authoring initial clinical and biomarker plans for Lead Optimization programs
- Development and execution of studies to validate clinical platforms utilizing established and novel biomarkers
- Provide clinical expertise for identification and validation of novel targets
- Safe and timely execution of Phase I studies
- Provide clear, timely communication and interpretation of study results to therapeutic area governance
- Contribute to assessment of internal and external opportunities identified by Business Development and Licensing
- Interface broadly with key functions throughout research sites around the world
Requirements
What you’ll need- MD/PhD or MD
- Clinical experience in and/or basic science background in internal medicine, pathology and/or oncology
- Demonstrated record of scientific scholarship and achievement
- Experience in oncology is preferred but not required
- Strong interpersonal, writing and presentation skills
- Ability to function in a team environment
- Clinical Board Certification preferred
- Prior experience in translational research and/or early clinical development preferred but not required
Benefits
Comp & perks- medical, dental, vision healthcare and other insurance benefits (for employee and family)
- retirement benefits, including 401(k)
- paid holidays
- vacation
- compassionate and sick days
ATS Keywords
✓ Tailor your resumeApplicant Tracking System Keywords
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Hard Skills & Tools
Early Clinical Development StrategyClinical Study ExecutionBiomarker DevelopmentTranslational ResearchScientific ScholarshipLead Optimization ProgramsClinical Platform Validation
Soft Skills
Interpersonal SkillsWriting SkillsPresentation SkillsTeam Collaboration
Certifications
Clinical Board Certification