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Principal Scientist, Clinical Research
MSDPrincipal Scientist leading early clinical development strategy for novel therapeutics in Translational Medicine. Collaborating with Discovery Sciences and late-stage Clinical Research teams to support drug development.
Posted 7/10/2026full-timeMassachusetts, New Jersey, Pennsylvania • 🇺🇸 United StatesMid-LevelSenior💰 $190,800 - $300,300 per yearWebsite
Core Competencies
Role fitCore Competencies
Use this summary to align your resume positioning with the role.
Demonstrates expertise in early clinical development strategy, including the design and execution of Phase I studies and the development of clinical and biomarker plans. Strong background in internal medicine, pathology, and oncology, with a focus on translational research and effective communication.
Highest-signal resume keywords
MD/PhD Or MDClinical Experience In Internal MedicineClinical Experience In PathologyClinical Experience In OncologyClinical Board Certification
ATS Keywords
Tailor your resumeApplicant Tracking System Keywords
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Hard Skills
Early Clinical Development StrategyClinical Study ExecutionBiomarker DevelopmentTranslational ResearchScientific ScholarshipLead Optimization ProgramsClinical Platform Validation
Soft Skills
Interpersonal SkillsWriting SkillsPresentation SkillsTeam Collaboration
Certifications & Qualifications
Clinical Board Certification
Industry Keywords
Phase I StudiesNovel TherapeuticsBiomarker PlansTherapeutic Area GovernanceBusiness DevelopmentLicensing
About the role
Key responsibilities & impact- Key member of an early development team, providing leadership in designing and executing early clinical development strategy
- Development and execution of early clinical strategy for novel therapeutics including authoring initial clinical and biomarker plans for Lead Optimization programs
- Development and execution of studies to validate clinical platforms utilizing established and novel biomarkers
- Provide clinical expertise for identification and validation of novel targets
- Safe and timely execution of Phase I studies
- Provide clear, timely communication and interpretation of study results to therapeutic area governance
- Contribute to assessment of internal and external opportunities identified by Business Development and Licensing
- Interface broadly with key functions throughout research sites around the world
Requirements
What you’ll need- MD/PhD or MD
- Clinical experience in and/or basic science background in internal medicine, pathology and/or oncology
- Demonstrated record of scientific scholarship and achievement
- Experience in oncology is preferred but not required
- Strong interpersonal, writing and presentation skills
- Ability to function in a team environment
- Clinical Board Certification preferred
- Prior experience in translational research and/or early clinical development preferred but not required
Benefits
Comp & perks- medical, dental, vision healthcare and other insurance benefits (for employee and family)
- retirement benefits, including 401(k)
- paid holidays
- vacation
- compassionate and sick days