Executive Director, Quantitative Pharmacology, Pharmacometrics

MSD

Team Leader at Merck's Quantitative Pharmacology Department, leading immunology portfolio decisions with a focus on drug development strategies. Overseeing a team in regulatory submissions and translational strategies.

Posted 5/3/2026full-timeWest Point • California, Massachusetts, New Jersey, Pennsylvania • 🇺🇸 United StatesLead💰 $231,900 - $365,000 per yearWebsite

About the role

Key responsibilities & impact

Leading a team of up to 7 QP2 scientists including people management, scientific and operational oversight, under the direction of the Therapeutic Area Head of Immunology
Leveraging end-to-end drug discovery/development and disease area expertise to independently provide day-to-day scientific oversight to individual contributors
Maintaining a comprehensive understanding of global regulatory expectations for all relevant modalities, shaping the clinical pharmacology regulatory strategy for selected immunology assets, and ensuring high quality regulatory documents (INDs, CSRs, CTDs)
Applies immunology knowledge and strategic thinking to identify, prioritize and develop enabling modeling platforms (disease, mechanistic, comparator models) at scale to create a differentiated immunology portfolio in an end-to-end manner in partnership with key internal/external collaborators
Implements quantitative clinical pharmacology, pharmacometrics and translational modeling efforts to streamline drug discovery and development strategies and integrating knowledge to inform key decisions
Engaging as an expert representative for QP2 in cross-functional and governance discussions, including business development and licensing evaluations
Setting priorities for direct reports and driving performance management, hiring and retention, staff development and training, and input into calibration and talent management processes
In partnership with the Therapeutic Area Head of Immunology, identify resource needs and contribute to resource allocation internally
Fostering a culture of collaborative and high-performing teaming

Requirements

What you’ll need

Ph.D./PharmD or equivalent degree with at least 12 years of experience
Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical/biomedical engineering, computational biology, or a related field
Demonstrated experience in regulatory strategies in Immunology including prior experience independently authoring and defending regulatory filings for marketing authorization (NDA/MAA)
Extensive experience in developing quantitative strategies for impacting pipeline decisions across different phases, and including complex modalities
Strong understanding of functional deliverables in drug R&D, with an ability to connect QP2 contributions to broader activities and needs
Demonstrated ability to lead interdisciplinary teams or taskforces, and to oversee and drive results through the work of others
Record of ability to operate in an inclusive and high-performance work environment applying enterprise ways of working principles including fostering collaboration and driving results, while managing ambiguity
Proficiency in written and verbal communication, interdisciplinary collaboration, and problem scoping and planning

Benefits

Comp & perks

medical, dental, vision healthcare and other insurance benefits (for employee and family)
retirement benefits, including 401(k)
paid holidays
vacation
compassionate and sick days

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

immunologyclinical pharmacologypharmacometricsquantitative strategiesregulatory filingsdrug discoverydrug developmentmodeling platformsbiopharmaceuticspharmaceutical sciences

Soft Skills

people managementstrategic thinkingperformance managementstaff developmentcollaborationleadershipcommunicationproblem solvingteam managementresource allocation

Certifications

Ph.D.PharmD