Zone Director

Mirum Pharmaceuticals, Inc.

Zone Director responsible for driving commercial performance and leadership in biotechnology company specializing in rare diseases. Ensuring execution excellence across the liver portfolio with a focus on teamwork and innovation.

Posted 6/6/2026full-timeRemote • Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Idaho, Illinois, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Minnesota, Mississippi, Missouri, Montana, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, Wisconsin, Wyoming • 🇺🇸 United StatesLeadWebsite

About the role

Key responsibilities & impact

Own and deliver Zone business performance across the liver portfolio with a strategic, big-picture mindset
Drive change and innovation
Develop and execute zone-specific business plans aligned to national strategy
Analyze market trends, competitive dynamics, and performance data to inform actions
Lead, coach, and develop first-line leaders to maximize team effectiveness
Build a strong leadership pipeline and succession plans
Foster a culture of accountability, engagement, and continuous improvement
Ensure consistent and high-quality execution of brand strategy in the field
Monitor KPIs and drive disciplined performance management
Identify and scale best practices across regions
Partner with Marketing, Market Access, Medical Affairs, Patient Services and Operations
Ensure alignment on strategy and coordinated execution
Provide field insights to inform brand planning and lifecycle strategy
Maintain strategic relationships with key opinion leaders (KOLs) and top accounts
Understand regional nuances in referral patterns and treatment pathways
Support teams in navigating complex access and reimbursement environments
Ensure all activities comply with regulatory, legal, and company policies
Model integrity and patient-first decision making
Reinforce a culture of compliance across the organization

Requirements

What you’ll need

Bachelor’s degree required; advanced degree preferred (MBA, etc.)
7+ years pharmaceutical/biotech experience, plus minimum of 5 years of leadership experience
Successful experience leading leaders (second-line leadership) highly desired
Significant rare disease and/or specialty experience
Experience in rare liver disease a plus
Proven success in product launches, ideally with first-in-class therapies and in competitive markets
Demonstrated ability to build, lead, train and develop high-performing teams
Proven success in sales leadership roles with the ability to inspire, influence and align teams
Experience navigating complex rare disease patient journeys, including diagnosis, referral pathways, and difficult access to therapies
Strong leadership presence with the ability to inspire, influence, and align teams
Strong understanding of market access, payer dynamics, and patient services
Demonstrated ability to lead in a matrixed organization
High integrity, ethical standards, and commitment to compliance
Thrives in a fast-paced, dynamic, and collaborative environment
Able to travel frequently, up to 70% overnight travel and has a valid drivers’ license

Benefits

Comp & perks

Equal Employment Opportunity (EEO)
Compliance with all Federal, State and Local laws

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

pharmaceutical experiencebiotech experienceleadership experienceproduct launchesmarket accesspayer dynamicspatient servicessales leadershipteam developmentcompliance

Soft Skills

strategic mindsetchange managementcoachingteam effectivenessaccountabilityengagementcontinuous improvementinfluenceinspirationintegrity

Certifications

Bachelor's degreeMBA