Senior Director – Business Modernization, Supply Chain

McKesson

Senior Director driving AI-enabled modernization across McKesson’s healthcare supply-chain operations. Leading product strategy, transformation programs, business cases, and organizational change.

Posted 8/9/2026full-timeRemote • Texas • 🇺🇸 United StatesSenior💰 $158,700 - $264,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in AI technologies and business transformation within the healthcare sector, with a strong focus on driving organizational change and developing strategic frameworks. Proven ability to lead complex projects, influence stakeholders, and execute high-impact initiatives that deliver measurable business outcomes.

Highest-signal resume keywords

AI TechnologiesBusiness TransformationFinancial AcumenChange ManagementStakeholder Engagement

ATS Keywords

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Hard Skills

Data AnalyticsFinancial ModelingROI AnalysisNPV CalculationIRR CalculationCapital AllocationProcess ImprovementProduct StrategyMachine LearningGenAI/LLM Capabilities

Soft Skills

Exceptional CommunicationMentoringCoachingInfluencing Without AuthorityProblem-Solving

Industry Keywords

HealthcarePharmaceutical ServicesOrganizational TransformationDesign ThinkingProgram Leadership

About the role

Key responsibilities & impact

Drive AI-enabled transformation across the North American Pharmaceutical Services organization
Challenge the status quo and orchestrate cross-functional modernization efforts
Partner with business leaders to execute high-impact AIM28 initiatives
Identify opportunities to adopt AI and advanced technologies and ensure measurable business outcomes
Serve as AI product strategist and voice of the business
Define product vision, problem statements, success metrics, and prioritized product roadmaps
Lead discovery, ideation, and first-principles problem-solving sessions
Translate business challenges into AI use cases, process requirements, and execution plans
Design future-state processes integrating machine learning and GenAI/LLM capabilities
Drive execution, remove roadblocks, manage interdependencies, and maintain program velocity
Develop business cases with Finance, establish KPIs, and track value realization
Lead workshops, communicate process changes, and promote adoption of AI-enabled processes
Develop and execute change management strategies
Engage and influence executives and drive organizational transformation
Support process improvement frameworks, governance, ethical AI standards, innovation, and build/buy/partner evaluations
Share insights and lessons learned across the organization
Perform other duties as assigned

Requirements

What you’ll need

Bachelor’s degree in business, engineering, technology, or related field or equivalent experience
Typically 10+ years of relevant experience
10+ years of progressive experience in business transformation, operations, or program leadership specific to healthcare
Fewer years may be required with relevant Master’s or Doctorate qualifications
Demonstrated expertise in business transformation, strategy, or relevant healthcare industry roles
Experience mentoring, coaching, and sharing best practices, particularly in design thinking and transformation
Strong financial acumen, including financial modeling such as ROI, NPV, IRR, and capital allocation
Deep expertise in AI technologies, data analytics, and their application to business transformation
Ability to lead complex projects and workstreams with diverse stakeholders
Ability to create frameworks and synthesize insights across multiple programs and initiatives
Exceptional communication skills for executive decision-making and alignment
Demonstrated success driving organizational change, resolving complex issues, and influencing senior stakeholders
Ability to influence without direct authority and drive cultural and organizational transformation
Ability to adapt to shifting priorities and responsibilities
Must be authorized to work in the United States without restriction or current/future employer sponsorship

Benefits

Comp & perks

Competitive compensation package
Annual bonus or long-term incentive opportunities may be offered
Remote work environment
Ability to travel 20%
Equal employment opportunities
Reasonable accommodation for job search or application