Vice President, Clinical Research

knownwell

Vice President of Clinical Research overseeing clinical trials at knownwell, a weight-inclusive healthcare provider. Responsible for trial infrastructure, sponsor relationships, and performance metrics.

Posted 7/27/2026full-timeBoston • Illinois, Massachusetts, New York • 🇺🇸 United StatesLead💰 $205,000 - $260,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive expertise in clinical trials operations, including budget management, sponsor relationship development, and compliance with GCP, ICH, and FDA regulations. Proven ability to lead teams, implement technology solutions, and drive performance metrics in a high-growth environment.

Highest-signal resume keywords

Clinical Trials OperationsGCP KnowledgeSponsor Relationship ManagementBudget ManagementTeam Building

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trials ManagementBudget DevelopmentP&L ManagementData Quality MonitoringRevenue ForecastingContract NegotiationSite Agreement ManagementKPI EstablishmentRisk IdentificationElectronic Data Capture

Soft Skills

LeadershipCollaborationCommunicationProblem-SolvingNegotiation

Tools & Technologies

CTMSETMFElectronic Data Capture Systems

Industry Keywords

Clinical TrialsPharmaceuticalBiotechIRB ProcessesFDA RegulationsICH GuidelinesMulti-Site TrialsSponsor RetentionEnrollment ProjectionsHigh-Growth Environment

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Assess the current state of the trials program - people, processes, documentation, and technology - and build a prioritized plan to close gaps while keeping active trials on track
Design and implement knownwell's end-to-end clinical trials operating model.
Select, implement, and own the technology stack required to professionalize the program - including CTMS, eTMF, and the transition from paper source to electronic data capture - without disrupting active trials during migration
Define the sponsor pipeline strategy — which therapeutic areas, which sponsors, which trial phases align with our patient population and care model
Own the business case and budget for trials as a program, including revenue projections and resource requirements
Protect and deepen existing sponsor relationships, sponsor retention and repeat business are as important as new pipeline development at this stage of the program
Identify, cultivate, and close relationships with pharmaceutical and biotech sponsors seeking multi-site primary care and metabolic health sites
Negotiate site agreements, budgets, and payment milestones
Hold accountability for the performance of all active trials across knownwell's clinic network — enrollment, data quality, monitoring readiness, and closeout — through the Director of Research and Clinical Trial Manager; the VP sets standards and removes barriers, not day-to-day task management.
Coordinate across knownwell's clinical, growth, operations, and technology teams to embed trial workflows into existing clinical infrastructure without disrupting care delivery
Manage relationships with CROs, IRBs, and regulatory bodies; own inspection readiness at all times
Define the org structure, hiring plan, and growth trajectory for the trials team
Own a trials P&L and report progress, risks, and financial performance to the CEO and Board
Establish full visibility into program costs, including staff time, clinical resource utilization, vendor spend, lab and imaging costs, and site-level overhead
Own the budget for the trials program, including annual operating budget, per-study budget development, and ongoing variance tracking; translate budget decisions into financial projections the CEO and Board can act on
Build and manage a milestone invoicing system that ensures knownwell invoices sponsors accurately and on time for every earned payment; identify and recover any milestones that have been missed or delayed under the current structure
Develop revenue forecasting by study and by sponsor, incorporating enrollment projections, milestone schedules, and contract terms; maintain a rolling 12-month revenue outlook
Establish service line KPIs, site performance metrics, and sponsor satisfaction benchmarks
Proactively identify risks — enrollment gaps, protocol deviations, sponsor issues — and resolve before they escalate

Requirements

What you’ll need

10+ years in clinical trials operations
Demonstrated track record of running concurrent trials across multiple sites
Strong working knowledge of GCP, ICH guidelines, FDA regulations, and IRB processes
Experience negotiating and managing sponsor and CRO relationships, including budgets and contracts
Proven team builder; you've hired and developed trials staff in resource-constrained environments
Financial fluency — you can build a budget, manage a P&L, and translate operational decisions into financial implications
Comfortable operating in an early-stage, high-growth environment

Benefits

Comp & perks

Medical, dental, and vision insurance
401K retirement plan with company match
Up to 20 days of PTO per year + company holidays
Up to 14 weeks of parental leave (12 for non-birthing parents)