Senior Director, Endometrial Cancer Brand Lead

Karyopharm Therapeutics Inc.

Senior commercial leader overseeing U.S. brand strategy and lifecycle management for endometrial cancer treatments.

Posted 6/9/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $270,000 - $315,000 per yearWebsite

About the role

Key responsibilities & impact

Own the U.S. EC brand strategy and multi-year commercial roadmap; deliver an annual Brand Plan/AOP with clear objectives, KPIs, milestones, and investment choices aligned to franchise and corporate priorities.
Define and evolve positioning, message platform, and customer value proposition; translate clinical and real-world evidence into differentiated, compliant claims and communications.
Lead lifecycle planning and strategic scenario work (e.g., competitive response, biomarker-driven opportunities, combination strategies, line-of-therapy expansion opportunities, and treatment sequencing dynamics), partnering with cross-functional leaders to evaluate options and trade-offs.
Drive U.S. EC launch strategy and readiness from pivotal data readout through launch execution, defining launch milestones, critical path, and cross-functional workstreams.
Develop customer segmentation and targeting strategy across key stakeholders, including gynecologic oncologists, medical oncologists, academic cancer centers, community oncology practices, integrated delivery networks, and key accounts.

Requirements

What you’ll need

BS/BA required; advanced degree preferred (MBA, PharmD, PhD, MPH, or equivalent)
12+ years of commercial biopharmaceutical experience, including 7+ years in oncology marketing
Launch, major lifecycle event, and/or new indication experience in oncology; solid tumor experience preferred
Experience in endometrial cancer, gynecologic oncology, or related oncology markets preferred
Proven success developing brand strategy and delivering commercial results
Strong understanding of U.S. market access, reimbursement, and oncology treatment landscapes
Experience leading cross-functional teams in a fast-paced biotech environment
Exceptional strategic thinking, analytical, communication, and executive presentation skills
Demonstrated ability to influence senior stakeholders and drive alignment across functions

Benefits

Comp & perks

medical
dental
vision
401(k)
and more
equity
potential to receive annual target bonuses

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

brand strategycommercial roadmapcustomer segmentationoncology marketinglifecycle planninglaunch strategyclinical evidencecompliancestrategic scenario workbiopharmaceutical experience

Soft Skills

strategic thinkinganalytical skillscommunication skillsexecutive presentation skillsinfluencing skillscross-functional leadershipalignment drivingstakeholder managementteam leadershipfast-paced environment adaptability

Certifications

BS/BAMBAPharmDPhDMPH