Distinguished Scientist, Biologics Discovery, Process Research Integrator

Johnson & Johnson

Lead scientific and strategic initiatives in biologics discovery at Johnson & Johnson. Focus on decision-making and risk mitigation in the development of biotherapeutics.

Posted 7/2/2026full-timeSpring House • Pennsylvania • 🇺🇸 United StatesSeniorLeadWebsite

About the role

Key responsibilities & impact

Serve as the scientific and strategic leader between Therapeutic Discovery & Supply (TDS) and Discovery teams.
Enable seamless end‑to‑end decision‑making for biologics programs and technical platforms.
Proactively identify and mitigate development risks during the discovery phase.
Ensure that structural, biophysical, expression, and developability insights are assessed and effectively integrated into Chemistry, Manufacturing and Controls (CMC) strategies and program planning.
Identify early opportunities to assess knowledge gaps to derisk program development.
Lead platform alignment efforts to ensure data and decisions are translatable across discovery and development.
Build out knowledge management and sharing systems to integrate knowledge across the teams.

Requirements

What you’ll need

PhD in Structural Biology, Biochemistry, Biophysics, Chemical or Biomedical Engineering, or a closely related field is required.
A minimum of 15 years of biopharmaceutical R&D experience spanning both Discovery and Development / CMC functions.
Deep technical expertise in at least one of the following areas: protein structure, developability principles, and expression considerations and the impact these have on CMC development.
Strong understanding of end‑to‑end biologics development, including the scientific and operational needs of CMC.
Proven ability to shape and implement large cross-functional projects in a matrixed environment to drive meaningful impact to the business.
Excellent communication, interpersonal, and scientific storytelling skills.
Experience supporting IND‑enabling or early clinical development efforts (preferred).
Familiarity with predictive modeling, sequence/structure analysis tools, or computational developability platforms (preferred).
Experience working across global teams or in high‑complexity program environments (preferred).

Benefits

Comp & perks

Inclusive work environment
Professional development opportunities

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Protein StructureDevelopability PrinciplesExpression ConsiderationsCMC StrategiesKnowledge Management Systems

Soft Skills

Excellent CommunicationInterpersonal SkillsScientific Storytelling