Director, Global Commercial Strategy – GI

Johnson & Johnson

Director of Global Commercial Strategy leading commercial strategy from early discovery to late-stage development within the GI portfolio. Fostering collaboration across teams to drive integrated strategies for innovative medicine.

Posted 6/30/2026full-timeHorsham • Pennsylvania • 🇺🇸 United StatesLeadWebsite

About the role

Key responsibilities & impact

Serve as the commercial lead for early-stage Compound Development Teams (CDTs)
Embed commercial strategy from discovery through proof-of-concept to ensure development plans are aligned with DAS roadmap and long-term portfolio value
Translate the DAS roadmap into actionable asset-level strategies by defining priority disease spaces, patient segments, clinical value drivers, differentiation requirements, and evidence needs across the early pipeline
Shape target product profiles (TPPs), indication sequencing, competitive positioning, and go/no-go criteria to support timely investment decisions and maximize probability of technical, regulatory, and commercial success
Provide commercial input into clinical trial design, endpoint selection, comparator strategy, patient enrichment, line-of-therapy positioning, and label-enabling evidence generation for priority GI assets
Drive portfolio prioritization across internal programs and external innovation opportunities
Evaluate external assets, combination strategies, and white-space opportunities that can accelerate or strengthen execution of the GI roadmap
Develop executive-ready recommendations for governance forums
Partner with late-development program teams to translate asset strategy into launch-ready commercial plans
Shape pre-launch planning across target product profile refinement, launch sequencing, brand positioning, evidence generation, stakeholder engagement, and readiness milestones
Lead competitive strategy and differentiation planning

Requirements

What you’ll need

A Bachelor’s degree is required
An advanced degree preferred, including MBA, PharmD, PhD, MD, or related scientific/business discipline
10+ years of progressive experience in pharmaceutical, biotech, or healthcare commercial strategy, marketing, business development, market access, medical affairs, R&D strategy, or related functions
Demonstrated experience developing commercial strategy for pipeline, early development, late-stage, and/or launch assets, ideally in immunology, gastroenterology, or specialty medicine
Strong understanding of drug development, clinical trial design, endpoints, regulatory considerations, evidence generation, market access, and global commercialization requirements
Strong strategic thinking, analytical rigor, and business acumen, with the ability to translate scientific, clinical, competitive, and market insights into clear commercial implications and actionable recommendations
Excellent written and verbal communication skills, including ability to develop executive-ready narratives, synthesize complex information, and present recommendations to senior leadership
Demonstrated leadership behaviors consistent with Our Credo and J&J leadership expectations, including accountability, collaboration, inclusion, agility, and enterprise mindset

Benefits

Comp & perks

inclusive work environment
equal opportunity employer
consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law
interview process that is inclusive of applicants’ needs

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Commercial StrategyClinical Trial DesignRegulatory ConsiderationsEvidence GenerationMarket AccessPortfolio PrioritizationCompetitive PositioningTarget Product Profile DevelopmentAnalytical RigorBusiness Acumen

Soft Skills

Strategic ThinkingExcellent CommunicationCollaborationAgilityInclusion

Certifications

MBAPharmDPhDMD