Clinical Data Manager II

Iovance Biotherapeutics, Inc.

Clinical Data Manager II assisting in end-to-end Data Management activities for Iovance Biotherapeutics cancer therapy. Responsible for data integrity, compliance, and collaboration with multi-disciplinary teams.

Posted 4/27/2026contractRemote • 🇺🇸 United StatesMid-LevelSenior💰 $62,000 - $70,000 per yearWebsite

About the role

Key responsibilities & impact

Ensure the integrity, accuracy and compliance of clinical trial data
Assist during a study database in RAVE to include but not limited to:
Review protocols for appropriate data capture including electronic Case Report Form (eCRF) design
Assist with the development of data edit check specifications and data listings
Perform User Acceptance Testing (UATs) of Electronic Data Capture (EDC) systems according to company processes
Assist with the review of migration reports to ensure database build accuracy
Perform reconciliation of data from external data sources against the clinical database
Perform Serious Adverse Event reconciliation activities according to SOPs and guidelines
Execute data cleaning and discrepancy management to ensure compliance with the protocol
Track and report study metrics to internal and external stakeholders
Create or update Data Management Plan (DMP), Data Review Plan (DRP), eCRF Completion Guidelines (eCCGs) and other Data Management required study documents
Perform database lock and freeze activities per company SOPs

Requirements

What you’ll need

At a minimum, Bachelor's degree required in the scientific or healthcare field
At least 5 years' experience in Data Management for the pharmaceutical / biotechnology industry, or equivalent experience in an FDA-regulated environment including study lead experience
Oncology experience is a must
RAVE database experience is preferable
Must have good time management skills and a proven ability to multitask
Possesses a comprehensive understanding of regulatory guidelines and industry standards (e.g., ICH/FDA guidance, CDISC standards, GCDMP, 21 CFR 11, MedDRA, WHO Drug Dictionaries, etc.) and their application to Data Management practice.
Attention to detail and the ability to work individually, within a multi-disciplinary team, as well as with external partners and vendors.
Possesses strong English language written and verbal communication skills.
Able to travel to off-site meetings or training seminars as needed.
Possesses solid computer system and technical skills with a strong ability to learn multiple computer applications.
Experience in Coding (MedDRA and WHODrug), Site and User Management and Lab Normal Range (LNR) entry in Rave is a plus
Must be able to work collaboratively in a fast-paced environment.

Benefits

Comp & perks

Health insurance
401(k) matching
Flexible work hours
Paid time off
Remote work options

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

data managementUser Acceptance Testing (UAT)data cleaningdiscrepancy managementdata reconciliationeCRF designdata edit check specificationscoding (MedDRA, WHODrug)database lockdatabase freeze

Soft Skills

time managementmultitaskingattention to detailcommunication skillscollaborationability to work independentlyability to work in a teamadaptabilityproblem-solvingstakeholder reporting