Senior Clinical Trial Manager, Research Alliances

Iovance Biotherapeutics, Inc.

Senior Clinical Trial Manager leading clinical projects and collaborations in cancer treatment at Iovance Biotherapeutics. Responsible for management of EAPs and Phase 4 studies.

Posted 4/22/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $165,000 - $185,000 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Oversee the timely activation, execution, and management of Expanded Access Programs (EAPs) that support commercial launch activities at authorized treatment centers
Leads the activities for the timely activation, execution, and management of Post Marketing study
Oversee the timely activation, execution, and management of ISTs/non-clinical research projects
Ensure Sunshine Act reporting data for lifileucel and Proleukin products across Research Alliances programs are collected
Works closely with Legal to initiate CDAs, clinical trial and service agreements, amendments and change orders for EAPs, Phase 4, Investigator-Sponsored and non-clinical collaborations.
Manages external contract research organizations involved with EAPs and Phase 4 who will have responsibility for site interaction, site monitoring, patient schedule management, data collection/management, central IRB interaction, and clinical site contracts.
Oversee drug supplies, co-therapies, and lab supplies for clinical and non-clinical collaboration studies and EAPs.
Reports to Iovance teams on study status, activity and site/vendor performance. Develops and maintains dashboards and trackers to communicate progress and risks.
Ensure that Investigative sites submit monthly enrollment logs, safety listings, database transfers and quarterly reports or as required in the study agreements.
Responsible for the writing and updating workflows, manuals, consent forms, and technical documents to support EAPs, Phase 4, ISTs/collaborations and non-clinical studies.
Organizes and documents decisions of routine meetings with internal teams, CROs and Investigator/research teams.
Collect and maintain essential regulatory documents.
Contribute and lead process improvements by updating or developing SOPs and Work Instructions.
Performs additional job-related duties as required to support successful program execution.
Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics.
Perform other miscellaneous duties as assigned.

Requirements

What you’ll need

Bachelor’s degree in health or science-related area with 7+ (Sr. CTM) or 5+ (CTM) years of clinical operations experience in the pharmaceutical or biotech area. Or an equivalent combination of education and relevant experience
Demonstrated ability to independently initiate and manage Expanded Access Programs and Phase 1–4 clinical trials
Proven track record of building and maintaining effective relationships with investigative sites and site personnel
Excellent written and verbal communication skills, with the ability to collaborate across internal and external stakeholders
Demonstrated ability to work independently, adapt to changing priorities, and manage multiple programs in a dynamic, result-driven environment
Knowledge of US and Global Regulations and Guidance (ICH-GCP, FDA-CFR)
Experience in data collection, review and monitoring Phase 1-4 clinical studies
Demonstrated experience leading phase 1-4 clinical trials and supporting ISTs.
Demonstrated success in managing clinical studies within timeline and budget.
Strong interpersonal communication (verbal and written) with the ability to build strong relationships with peers and partners within and across functional teams to engage in high performance.
In-depth knowledge of Microsoft Office, including MS Word, MS Excel, MS PowerPoint, and MS Outlook
Previous experience with EDC systems (eClinical, Medidata RAVE, InForm), and electronic Trial Master File systems
Requires working knowledge of Good Clinical Practices, Food and Drug Administration regulatory reporting requirements, and the regulations and laws governing the pharmaceutical industry (e.g., compliance, Sunshine Act).

Benefits

Comp & perks

🌐 Worldwide ❌ Jobs You've Hidden ⭐️ Saved Jobs ✅ Applied Jobs ✉️ Email Alerts 👤 Account Iovance Biotherapeutics, Inc. Website LinkedIn All Job Openings 501 - 1000 employees Founded 2014 🧬 Biotechnology 💊 Pharmaceuticals ⚕️ Healthcare Insurance Biotechnology
Pharmaceuticals
Healthcare Insurance Iovance Biotherapeutics, Inc. is pioneering a transformational approach to treating cancer by harnessing the human immune system's ability to recognize and attack diverse cancer cells in each patient. The company focuses on T-cell-based immunotherapy, specifically Tumor Infiltrating Lymphocyte (TIL) therapy, which involves reinvigorating a patient’s TILs to fight cancer. Iovance's TIL therapy is being investigated in clinical trials across multiple advanced solid tumor cancers. Additionally, the company is advancing genetically modified TIL therapies and exploring potential applications of PBL (peripheral blood lymphocyte) therapy for blood cancers. As a leader in cell therapy, Iovance owns a state-of-the-art Cell Therapy Center in Philadelphia for manufacturing their therapies using proprietary GMP. The company is at the forefront of developing personalized and patient-specific cancer treatments. Senior Clinical Trial Manager, Research Alliances Job not on LinkedIn 🔥 0 minutes ago 🇺🇸 United States – Remote 💵 $165k - $185k / year ⏰ Full Time 🟠 Senior 🧪 Clinical Research Apply Now Find Hiring Managers Customize resume for this job Report problem ☆ Save ☑️ Mark as applied ❌ Hide 📋 Description
Oversee the timely activation, execution, and management of Expanded Access Programs (EAPs) that support commercial launch activities at authorized treatment centers
Leads the activities for the timely activation, execution, and management of Post Marketing study
Oversee the timely activation, execution, and management of ISTs/non-clinical research projects
Ensure Sunshine Act reporting data for lifileucel and Proleukin products across Research Alliances programs are collected
Works closely with Legal to initiate CDAs, clinical trial and service agreements, amendments and change orders for EAPs, Phase 4, Investigator-Sponsored and non-clinical collaborations.
Manages external contract research organizations involved with EAPs and Phase 4 who will have responsibility for site interaction, site monitoring, patient schedule management, data collection/management, central IRB interaction, and clinical site contracts.
Oversee drug supplies, co-therapies, and lab supplies for clinical and non-clinical collaboration studies and EAPs.
Reports to Iovance teams on study status, activity and site/vendor performance. Develops and maintains dashboards and trackers to communicate progress and risks.
Ensure that Investigative sites submit monthly enrollment logs, safety listings, database transfers and quarterly reports or as required in the study agreements.
Responsible for the writing and updating workflows, manuals, consent forms, and technical documents to support EAPs, Phase 4, ISTs/collaborations and non-clinical studies.
Organizes and documents decisions of routine meetings with internal teams, CROs and Investigator/research teams.
Collect and maintain essential regulatory documents.
Contribute and lead process improvements by updating or developing SOPs and Work Instructions.
Performs additional job-related duties as required to support successful program execution.
Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics.
Perform other miscellaneous duties as assigned. 🎯 Requirements
Bachelor’s degree in health or science-related area with 7+ (Sr. CTM) or 5+ (CTM) years of clinical operations experience in the pharmaceutical or biotech area. Or an equivalent combination of education and relevant experience
Demonstrated ability to independently initiate and manage Expanded Access Programs and Phase 1–4 clinical trials
Proven track record of building and maintaining effective relationships with investigative sites and site personnel
Excellent written and verbal communication skills, with the ability to collaborate across internal and external stakeholders
Demonstrated ability to work independently, adapt to changing priorities, and manage multiple programs in a dynamic, result-driven environment
Knowledge of US and Global Regulations and Guidance (ICH-GCP, FDA-CFR)
Experience in data collection, review and monitoring Phase 1-4 clinical studies
Demonstrated experience leading phase 1-4 clinical trials and supporting ISTs.
Demonstrated success in managing clinical studies within timeline and budget.
Strong interpersonal communication (verbal and written) with the ability to build strong relationships with peers and partners within and across functional teams to engage in high performance.
In-depth knowledge of Microsoft Office, including MS Word, MS Excel, MS PowerPoint, and MS Outlook
Previous experience with EDC systems (eClinical, Medidata RAVE, InForm), and electronic Trial Master File systems
Requires working knowledge of Good Clinical Practices, Food and Drug Administration regulatory reporting requirements, and the regulations and laws governing the pharmaceutical industry (e.g., compliance, Sunshine Act). Apply Now 📊 Check your resume score for this job Improve your chances of getting an interview by checking your resume score before you apply. Check Resume Score Similar Jobs Clinical Research Physician – Ophthalmology 🕒 Yesterday Eli Lilly and Company 10,000+ employees 💊 Pharmaceuticals Website LinkedIn All Job Openings Clinical Research Physician developing and conducting global clinical trials for ophthalmologic products. Utilizing medical expertise to ensure product development from inception to commercialization. 🇺🇸 United States – Remote 💵 $198k - $389.4k / year ⏰ Full Time 🟡 Mid-level 🟠 Senior 🧪 Clinical Research 🦅 H1B Visa Sponsor Clinical Trial Manager 🕒 2 days ago Foresight Diagnostics Inc. 11 - 50 Website LinkedIn All Job Openings Clinical Trial Manager overseeing operational execution of clinical studies in precision oncology. Managing timelines, quality, and partner relationships from study protocol implementation to close-out. 🇺🇸 United States – Remote 💵 $150k - $170k / year ⏰ Full Time 🟡 Mid-level 🟠 Senior 🧪 Clinical Research Clinical Scientist 🕒 5 days ago Worldwide Clinical Trials 1001 - 5000 🧬 Biotechnology 💊 Pharmaceuticals ⚕️ Healthcare Insurance Website LinkedIn All Job Openings Clinical Scientist leading the review and assessment of clinical data for oncology trials at Worldwide. Collaborating with cross-functional teams to ensure high-quality deliverables and insights. 🇺🇸 United States – Remote ⏰ Full Time 🟠 Senior 🔴 Lead 🧪 Clinical Research 🦅 H1B Visa Sponsor Senior Principal Biostatistician 🕒 5 days ago ICON plc 10,000+ employees 💊 Pharmaceuticals 🧬 Biotechnology ⚕️ Healthcare Insurance Website LinkedIn All Job Openings Senior Principal Biostatistician leading Phase I-II clinical trials at ICON, overseeing statistical activities and mentoring junior statisticians. 🇺🇸 United States – Remote ⏰ Full Time 🟠 Senior 🧪 Clinical Research Senior Clinical Scientist 🕒 5 days ago ICON plc 10,000+ employees 💊 Pharmaceuticals 🧬 Biotechnology ⚕️ Healthcare Insurance Website LinkedIn All Job Openings Clinical Scientist at ICON designing and conducting clinical studies to advance new therapies. Collaborating with multidisciplinary teams to prepare regulatory submissions and study reports. 🇺🇸 United States – Remote ⏰ Full Time 🟠 Senior 🧪 Clinical Research View More Clinical Researcher Jobs 🌐 Worldwide Built by Lior Neu-ner. I'd love to hear your feedback — Get in touch via DM or support@remoterocketship.com Search Search Jobs by country Search jobs by city Search jobs by job title Search entry-level jobs Search junior-level jobs Search senior-level jobs Search jobs by tech stack Search jobs by contract type Search remote internships Search remote part-time jobs Remote jobs Anywhere in the World Companies Hiring Anywhere in the World Companies Hiring Sales People Anywhere in the World Companies Hiring Software Engineers Anywhere in the World Resources Advice Tips for finding remote jobs Interview questions and answers Resume examples Cover letter examples Post a job Affiliates Privacy policy Terms of service Job board SEO course AI Apply Copilot OpenClaw job finder Jobs by Country Remote jobs anywhere in the world (Worldwide remote jobs) Remote jobs United States Remote jobs Australia Remote jobs Brazil Remote jobs Canada Remote jobs France Remote jobs Ireland Remote jobs Germany Remote jobs Netherlands Remote jobs Spain Remote jobs UK Popular Jobs Remote data analyst jobs Remote customer support jobs Remote executive assistant jobs Remote marketing jobs Remote product designer jobs Remote product manager jobs Remote project manager jobs Remote recruiter jobs Remote sales jobs Remote software engineer jobs Jobs by Type Remote full-time jobs Remote part-time jobs Remote contract jobs Remote internship jobs Remote entry-level jobs Remote jobs with no experience required Remote junior jobs (1-3 years of experience) Digital nomad jobs Remote jobs with no degree required Freelance remote jobs Temporary remote jobs Remote jobs hiring now Stay at home mom jobs

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Hard Skills & Tools

clinical operationsExpanded Access ProgramsPhase 1-4 clinical trialsdata collectionmonitoringproject managementregulatory document managementSOP developmentworkflow writingprocess improvement

Soft Skills

communicationrelationship buildingindependent workadaptabilitymulti-taskingcollaborationinterpersonal skillsproblem-solvingleadershiporganizational skills