ICON plc

Communications

• Reviewing source materials, including clinical trial protocols and relevant external sources.
• Developing scripts and visuals that are scientifically accurate, technically precise, and clearly aligned with client needs.
• Collaborating closely with graphic designers to develop engaging materials, including mechanism of action animations and eligibility criteria case studies for Health Care Professionals.
• Developing clear and informative content for potential Clinical Trial Participants, helping them understand the clinical trial and what taking part may involve.
• Creating content and storyboards related to disease pathophysiology and drug mechanisms of action for our high-quality educational products.
• Contributing to continuous improvement initiatives, helping to identify potential improvements and innovative approaches to the design and development of training products within FIRECREST.

Scientific Communication Advisor

3D Artist

• Collaborate with cross-functional teams to create 3D graphics, animations, and visualizations for clinical trial materials.
• Collaborate with marketing, content, and design teams to align video content with broader marketing strategies.
• Design motion graphics, transitions, and other visual elements to enhance storytelling.
• Translate complex medical data into compelling visuals.
• Work with Pharmacologist team to understand complex content.
• Create clear and engaging storyboards.
• Produce effective instructional videos.
• Implement client edits for product improvement.
• Develop 3D graphics for various projects.
• Contribute to FIRECREST’s 3D modeling approach.

3D Motion Designer

Manager

• Leading and managing a team of data analysts and data scientists, providing direction and support to ensure effective application of data analytics and advanced modeling techniques.
• Developing and implementing analytics strategies to address business needs, including predictive modeling, statistical analysis, and data visualization, to support decision-making and optimize performance.
• Collaborating with cross-functional teams, including clinical operations, IT, and business units, to integrate analytics solutions into operational workflows and ensure alignment with strategic objectives.
• Monitoring and evaluating analytics performance metrics, identifying trends and insights, and driving initiatives to enhance the effectiveness and efficiency of data-driven solutions.
• Staying abreast of industry trends, emerging technologies, and best practices in data analytics, and applying this knowledge to innovate and advance our analytics capabilities.

Senior Manager, Data & Applied Analytics

Research Analyst

• Your compassion and dedication will be at the forefront as you take vital signs and perform phlebotomy on study subjects, ensuring their comfort and well-being throughout the research process.
• You will be entrusted with following our clients' protocols when conducting vital sign assessments and phlebotomy procedures.
• Joining us means being part of a collaborative environment where your active participation in meetings and other assignments will be valued and recognized.
• Your role will extend beyond the clinical aspects as you chaperone study subjects during their breaks outside, offering personalized care and ensuring their comfort.

Phlebotomist, Medical Research Associate

• May lead or support a study or studies, depending on size/complexity.
• Operational point of contact for trial execution and all trial deliverables
• Manages all HQ Operational Activities, including:
• Establishes, leads and manages Clinical Trial Team (CTT)
• Supports clinical (drug/vaccine) supplies planning
• Manages deployment and interactions with external vendors (e.g., IVRS, PRO)
• Initiates planning for Investigator meeting and protocol training.
• Plans and assesses protocol ancillary supplies
• Completes trial set-up and maintains CTMS
• Schedules, prepares for, and leads the Recruitment Planning Meeting for the CTT
• Initiates recruitment/retention planning & enrollment tracking
• Responsible for tracking study related details (e.g., specimens, queries)
• Oversees protocol training activities including IMs and CRAs training meetings
• Ensures appropriate postings to investigative site portals
• Responsible for operational deliverables in preparation for site ready, country allocation and achievement of recruitment targets (with input from others)
• Point of escalation for study related operational issues
• Responsible for operational details at Operational Reviews
• Responsible for creating and maintaining project schedule and collaborating with Program Lead
• Sets up and maintains Trial Master File (eTMF)
• Ensures alignment of budget with protocol needs
• Responsible for executing protocol within the budget
• Responsible for creating and maintaining ADI logs
• Develops Site Monitoring Plan (SMP) with input from the monitoring excellence group
• Develops study related manuals (e.g., administrative binder, lab manuals)
• Manages Emergency Unblinding (EUB) Call Center activities
• Co-authors newsletters with CS
• Approves contracts, invoice payments and change orders for vendors, as necessary
• Responsible for end of study reconciliation (clinical & ancillary supplies)
• Oversees all HQ close-out tasks
• Responsible for ongoing monitoring of trial activities, e.g. dashboards, tracking
• Supports CS activities as needed to achieve CTT deliverables
• Interface with External Data Coordination and Data Management
• Responsible for quality control and inspection readiness at all times
• Responsible for risk assessment, mitigation planning and execution

Senior Study Manager

Operations

• Collaborating with subject matter experts to understand presentation objectives, audience needs, and key messaging.
• Designing and formatting presentations using PowerPoint or other presentation software, incorporating graphics, charts, and multimedia elements to enhance visual appeal and effectiveness.
• Developing templates and style guides to maintain consistency and branding standards across all presentations.
• Providing guidance and support to presenters on best practices for delivering impactful presentations, including storytelling techniques and slide design principles.
• Managing multiple projects simultaneously and delivering presentations on time and within budget.
• Staying current on presentation design trends and software tools to continually enhance the quality and effectiveness of presentations.

Medical Operations Virtual Meeting Moderator

• Assist the SM Study Lead and study team with the operational conduct of clinical studies (e.g., CTT minutes, clinical supplies planning/tracking, lab specimen tracking, imaging data reconciliation, status update reports, study closeout activities)
• May support a single study or multiple studies
• May lead a study with limited scope (e.g., Survival Follow-up)
• May be responsible for tracking study timelines and will be proficient in project management tools
• May interact with internal and external stakeholders (study sites, vendors, committees, etc.) in support of clinical study objectives.

Study Manager – Oncology

• Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.
• Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.
• Collaborating with investigators and site staff to facilitate smooth study conduct.
• Performing data review and resolution of queries to maintain high-quality clinical data.
• Contributing to the preparation and review of study documentation, including protocols and clinical study reports

Clinical Research Associate – Sponsor Dedicated

Clinical Research

• Accountable for the full spectrum of investigator engagement from identification and qualification through enrollment, and support database lock, and study closeout
• Serve as a clinical trial scientific ambassador, ensuring investigators deeply understand protocol intent, scientific rationale, and patient eligibility requirements
• Develop and sustain strategic, high-trust relationships with investigators that span trials and therapeutic areas
• Influence enrollment by co-creating tailored recruitment strategies aligned with site capabilities, patient population realities, and study objectives
• Proactively find opportunities to reach new patients, accelerate enrollment and increase impact at priority sites, including for example, novel site models, community-based research initiatives etc
• Capture and elevate critical insights from sites to optimize feasibility, protocol design, and study conduct
• Lead site-level strategy and risk planning to ensure strong and predictable enrollment and data delivery
• Leverage performance metrics to anticipate issues, intervene decisively, and maintain momentum toward clinical milestones
• Drive inspection readiness as a continuous discipline across sites
• Collaborate across functions and with vendor partners to resolve operational barriers, ensuring delivery with speed and quality
• Maintain advanced understanding of local treatment paradigms and standard of care to influence strategic country/site selection and protocol localization
• Provide oversight and quality assurance for vendor monitoring, escalating risks proactively
• Cultivate a portfolio of strategically aligned, high-impact investigators who consistently prioritize client trials
• Enable an exceptional investigator experience by being a responsive, knowledgeable, and valued scientific partner
• Collaborate cross-functionally (e.g., Medical, Clinical, Study Delivery) to align on trial and site priorities, troubleshooting challenges with urgency and creativity
• Conduct data-informed site prospecting and prioritization, contributing to trial competitiveness and regional strategic execution
• Maintain scientific fluency and therapeutic expertise to lead meaningful, solutions-focused discussions with site personnel
• Act as a key liaison between field teams, vendors, and investigators, ensuring alignment, shared purpose, and continuous knowledge transfer
• Partner closely with field team colleagues to elevate the investigator and site experience, ensuring seamless collaboration and improving enrollment outcomes and Investigator relationships

Clinical Research Lead – Site Engagement

• Leading the preparation, submission, and maintenance of regulatory documents for EU CTIS submissions.
• Providing expertise and guidance on regulatory requirements and standards to internal teams.
• Interfacing with regulatory agencies to address inquiries, submissions, and approvals.
• Monitoring changes in regulations and guidelines to ensure compliance and mitigate risks.
• Collaborating cross-functionally to support regulatory aspects of clinical trial planning and execution.

CTIS Submission Manager

Data Scientist

• Demonstrate in-depth knowledge across two or more areas: Clinical Data Management Systems (CDMS), Data validation, Data ingestion and extraction, Risk-based analytics.
• Apply full understanding of Software Development Lifecycle (SDLC) methodologies.
• Support colleagues with complex clinical trial programming concepts and solutions.
• Develop and maintain analytics solutions including cross-page visualizations and information models.
• Write R and Python scripts as required.
• Act as primary point of contact during study setup for system programming-related queries.
• Independently review database specifications and program one or more CDMS/EDC systems.
• Program medium-to-high complexity data ingestion pipelines, CDMS solutions, risk management outputs, custom reports and analytics programs.
• Design and build eCRF screens per protocol specifications.
• Perform data extracts and develop data transfer programs.
• Communicate analytics requirements and technical solutions clearly to stakeholders.
• Oversee complete SDLC for assigned programming deliverables.
• Proactively identify and mitigate project risks; escalate issues impacting scope, timelines, or budget.
• Ensure quality of deliverables through formal QC and validation processes.
• Provide input to revenue forecasting and resource planning activities.

Lead Clinical Data Scientist, Programmer

Project Manager

• Developing and managing detailed project plans, including timelines, budgets, and resource allocation to ensure successful project delivery.
• Leading cross-functional project teams, coordinating efforts to meet project objectives, and facilitating effective communication and collaboration.
• Monitoring project progress, identifying potential risks and issues, and implementing strategies to address challenges and keep projects on track.
• Engaging with stakeholders to manage expectations, provide updates, and ensure alignment with project goals and organizational objectives.
• Preparing and presenting project reports, status updates, and performance metrics to senior management and other stakeholders.

Global Project Manager

Compliance

• Contributing to regulatory strategy development for clinical programmes, including plans for health authority interactions and submissions.
• Preparing, reviewing, and coordinating regulatory documents such as clinical trial applications, briefing packages, and responses to health authority questions.
• Interpreting and applying relevant regulations, guidelines, and precedents to support compliant study design and execution.
• Collaborating with clinical, safety, CMC, and other cross-functional teams to ensure alignment of regulatory content and messaging.
• Monitoring changes in the regulatory environment and providing guidance on potential impact to programmes and submissions.
• Supporting regulatory interactions and meetings, including preparation of materials and documentation of outcomes.

Regulatory Scientist

• Oversee the clinical portion of the budget to ensure efficient resource allocation.
• Develop monitoring plans and tools, ensuring effective study oversight.
• Train and mentor Clinical Research Associates (CRAs) to optimize their performance.
• Drive enrollment and lead study start-up activities, adhering to timelines.
• Review trip reports and implement corrective and preventative action plans when necessary.
• Foster productive relationships with Sponsors, vendors, and cross-functional teams.

Senior Clinical Trial Manager – Sponsor Dedicated

• Plan and manage all aspects of clinical trials, ensuring adherence to timelines, budget, and quality standards.
• Collaborate with cross-functional teams to establish and implement clinical trial protocols and procedures.
• Build and manage strong relationships with trial investigators and stakeholders.
• Ensure all trials are conducted in compliance with local, national, and international regulations and ethical guidelines.
• Problem-solve and make critical decisions regarding trial design, vendor selection, and risk management.