Senior Clinical Scientist

ICON plc

Clinical Scientist designing and conducting clinical studies at ICON, a global healthcare organization. Collaborating with teams to develop innovative treatments and improve patient outcomes.

Posted 6/25/2026full-timeRemote • Pennsylvania • 🇺🇸 United StatesSeniorWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Contribute to the development and creation of clinical trial protocols following high scientific and clinical standards and applicable regulations
Contribute to the identification, formulation and implementation of amendments to the clinical protocol, in close collaboration with clinical lead
Contribute to the creation of study-level documents, including preparation of clinical sections of key regulatory documents, such as Investigator’s Brochures, briefing books, safety updates and submission dossiers
Contribute to the review and writing of clinical trial documents for CTR activities, and publications (as applicable)
Support pharmacovigilance activities (e.g. contributing to creation and review of aggregate reports, patient narratives and attendance of pharmacovigilance monitoring meetings)
Support regulatory activities (preparation of meetings with regulatory agencies)
Produce training materials, share best practices and provide training to the broader clinical trial teams
Support preparation and (if applicable) participate in study level meetings (i.e. - Investigator Meetings, Data Monitoring meetings, and others)
Support and guide the development of data review strategy, ensuring that protocol-level deviations, eligibility criteria, study assessments & other aspects of the protocol are implemented consistently across the study (across countries/ sites)
Includes support for Case Report Form (CRF) development, and implementation of data capture tools
Deep expertise to perform in depth and high-quality clinical data review, to identify clinical data insights through ongoing patient level review and trends analysis to support Interim Analysis, Database and Post Lock activities and resolution of scientific & medical issues throughout the study lifecycle
Work to improve the quality of reviews and insights with an emphasis on subject safety and eligibility, data integrity, trend identification, analysis and remediation, and identification of cases for medical review
Provide insights to and facilitate data review process improvements by identification of redundant reports, implementation of innovative data analysis processes and tools, and their continuous improvement
For all these tasks, work in close collaboration and alignment with clinical development lead
Ensure all questions / issues requiring medical oversight are brought to the attention of the clinical development lead

Requirements

What you’ll need

Advanced degree in life sciences/ healthcare or clinically relevant degree
Minimum 8+ years' experience as a Clinical Scientist Oncology therapeutic area expertise required, preferably in Phase 1b/2 clinical research environment
Strong working knowledge of Good Clinical Practice (GCP) and drug development processes
Preferred knowledge of set-up, organization and execution of global clinical studies in a pharmaceutical company or contract research organization (CRO) environment
Sound knowledge of principles of clinical data collection and reporting with a demonstrated ability to use typical systems and tools (e.g., EDC systems, Excel, etc.) for data collection, analysis and reporting
Demonstrated knowledge to drive continuous improvement of processes, systems and tools
Experience to work in a matrix, with high level of ability to informally influence and collaborate without authority
High flexibility and adaptive working style, ability to work on several tasks at the same time
Ability to work effectively under high time pressure, while maintaining high quality standards
Ability to effectively prioritize tasks, and implement accordingly
High proficiency in English (written and spoken)

Benefits

Comp & perks

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways

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Hard Skills & Tools

clinical trial protocolsclinical data reviewdata analysisregulatory documentspharmacovigilanceGood Clinical Practice (GCP)clinical data collectiondata capture toolsInterim AnalysisPhase 1b/2 clinical research

Soft Skills

collaborationflexibilityadaptabilityprioritizationinfluence without authoritytime managementcommunicationtrainingprocess improvementproblem-solving