Project Manager

ICON plc

Project Manager leading global oncology clinical trials at ICON. Responsible for delivery strategy, vendor management, compliance, and collaboration across matrix teams.

Posted 5/23/2026full-timeRemote • Pennsylvania • 🇺🇸 United StatesMid-LevelSeniorWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Accountable for the global study delivery strategy (e.g., country selection, diversity, patient engagement strategy, recruitment plan, etc.) and for overall study deliverables
Drive assessment, selection, engagement, management, and oversight of appropriate vendors
Ensure compliance with ICH/GCP guidelines, all applicable laws and regulations, and sponsor SOPs, for all products and services delivered for their designated studies
Make decisions which balance risk/benefit with clear understanding of impact on the study and project; takes action to mitigate risk where appropriate
Work with matrix partners, asset lead and/or manager to develop and manage study level budget within project allocation
Preparation of materials for governance and / or financial review cycles and provide expert clinical operational input into protocol development
Lead and conduct investigator meetings and other study related meetings and participate in governance meetings as necessary
Identify and communicate resource gaps for assigned studies
Lead risk management and quality efforts to ensure study compliance and continual inspection readiness
Lead / contribute to ways of working and process improvement initiatives
Encourage others within matrix and line teams to seek alternative perspectives and develop solutions
Partner with Data Management and Clinical Sciences to develop the data cleaning strategy for the study and collaborate with Oncology aligned staff in global functions to deliver the Clinical Study Report
Work with the Oncology patient councils to develop patient centric documents and address patient burden

Requirements

What you’ll need

Bachelor’s degree in life sciences or related discipline
Extensive clinical development experience that is equivalent to 6 years as a global study leader with proven experience in driving operational study delivery to time, cost, and quality within the pharmaceutical industry or CRO environment
Proven operational experience leading global oncology clinical trials and knowledge of essential global regulatory guidelines and ICH/GCP
Proactively identify and resolve issues to ensure timely study delivery to quality, timelines, and budget
Proven leadership skills, influencing and negotiation skills
Demonstrated experience leading in the matrix environment to deliver projects, develop clinical plans and manage change
Oncology phase III global registrational study leadership experience preferred
Proven clinical development experience across all phases of development (I-IV)
Experience of innovative trial design (platform, basket, umbrella, adaptive designs) and decentralized trials (DCT) initiatives preferred.
Highly developed communication skills appropriate to the target audience, promoting effective decision-making where necessary and ability to manage conflict
Proven expertise in the proactive identification of issues which may impact clinical programs coupled with the ability to contribute to solutions affecting cross-functional matrix teams
Creative thinker able to modernize approach to clinical delivery, leverage externally.

Benefits

Comp & perks

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical developmentglobal study deliveryoncology clinical trialsregulatory guidelinesICH/GCPinnovative trial designdecentralized trialsrisk managementbudget managementdata cleaning strategy

Soft Skills

leadershipinfluencingnegotiationcommunicationproblem-solvingconflict managementcreative thinkingcollaborationdecision-makingprocess improvement