Senior Clinical Trial Manager

ICON plc

Senior Clinical Trial Manager at ICON, ensuring high-quality trial delivery and overseeing local trial management processes. Collaborating with cross-functional teams and managing trial excellence at the country level.

Posted 4/25/2026full-timeRemote • Pennsylvania • 🇺🇸 United StatesSeniorWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Accountable for ensuring top-quality end-to-end trial delivery at a country level.
Managing the consistency of Local Trial Management duties and processes.
Serving as the country-level single point of contact on the study for internal partners.
Managing and overseeing Central IRB and other local vendors including set up of vendor purchase orders, invoice review and approval, and change-orders.
Execution of local milestones from feasibility through study close out.
Resourcing of country-level roles, including support with transitions.
Inspection Readiness and AQR at the country level.
Close collaboration with assigned Local Trial Managers, Lead Site Manager, Site Managers, Clinical Trial Associates, and Site Contract Managers.
Efficient communication with Clinical Trial Managers and Global Trial Leader to oversee trial excellence.
Conducting country level ad hoc meetings during any phase of the study to address unexpected circumstances.

Requirements

What you’ll need

BA/BS degree
Degree in a health or science related field
3 - 5+ years of trial end to end management experience
Start-up & Database Locks/Cleaning experience preferred
Oncology Solid Tumor experience required
Specific therapeutic area experience may be required depending on the position.
Strong working knowledge of ICH-GCP, company standard operating procedures, local laws and regulations, assigned protocols and associated protocol specific procedures.
Strong IT skills in appropriate software and company systems.
Willingness to travel with occasional overnight stay away from home according to business needs.
Proficient in speaking and writing the country language and English.
Good written and oral communication skills as appropriate

Benefits

Comp & perks

Various annual leave entitlements
A range of health insurance offerings to suit you and your family’s needs.
Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being.
Life assurance
Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

trial managementfeasibility studiesdatabase locksdata cleaningoncologysolid tumorsICH-GCPprotocol managementlocal laws and regulationsstudy close out

Soft Skills

communicationcollaborationproblem-solvingleadershiporganizational skillsinspection readinessadaptabilityteamworkinterpersonal skillsmeeting facilitation

Certifications

BA/BS degreedegree in health-related fieldGCP certification