Principal Engineer, Cloud Ops

Iambic Therapeutics

Cloud Ops Engineer at Iambic Therapeutics managing Cloud Ops and infrastructure for drug discovery. Collaborating with teams on scalable AWS infrastructure and mentoring peers.

Posted 5/21/2026full-timeBoston • Massachusetts • 🇺🇸 United StatesLeadWebsite

Tech Stack

Tools & technologies

AnsibleAWSCloudDistributed SystemsDNSDockerKubernetesPackerTCP/IPTerraform

About the role

Key responsibilities & impact

Support and contribute to the Cloud Ops roadmap, aligning infrastructure initiatives with business priorities.
Provide technical leadership and drive architecture decisions across platform and infrastructure teams.
Lead the design and evolution of scalable, highly available AWS cloud infrastructure.
Build and operate production systems with a strong focus on reliability, performance, and cost efficiency.
Design and manage cloud networking (VPN, VPC, routing, DNS, load balancing, secure connectivity).
Implement Infrastructure as Code (Terraform) and automate provisioning and operations.
Troubleshoot complex issues across distributed systems, including networking and performance bottlenecks.
Apply security best practices and support the ISO 27001 compliance frameworks.
Improve observability, CI/CD pipelines, and overall operational maturity.
Mentor engineers in Cloud Services and influence Cloud Ops best practices across the org.

Requirements

What you’ll need

Minimum of 12 years of related experience with a bachelor’s degree; or 10 years and a master’s degree; or equivalent experience.
Strong understanding of CI/CD pipelines.
Strong Infrastructure as Code skills – for example in Docker, Packer/Ansible and Terraform/Terragrunt.
Strong understanding of AWS services and underlying technologies such as AWS IAM service and managing Kubernetes as a service (AWS EKS) including managing zero-downtime upgrades and debugging issues with deployments, controllers, etc. Deployed in the cluster.
Strong understanding of computer networks:
TCP/IP protocols.
IP block allocation across an organization.
Routing and VPN protocols.
AWS networking: VPCs, Transit Gateways, Customer Gateways, VPNs, flow logs, security groups, NACLs, etc.
Cloudflare networking experience.
Understanding of issues facing ML deployments including model training and inference challenges.
Ability to communicate with a variety of teams including IT, Computational Scientists, Software Developers, Cloud Ops and ML engineers

Benefits

Comp & perks

We offer industry leading competitive pay
company paid healthcare
flexible spending accounts
voluntary life insurance
401K matching
uncapped vacation
onsite gym
dining

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

AWSInfrastructure as CodeTerraformDockerAnsibleKubernetesCI/CD pipelinesTCP/IPcloud networkingISO 27001

Soft Skills

technical leadershipmentoringcommunication