Associate Director, Quantitative Systems Pharmacology

GSK

Associate Director developing and applying Quantitative Systems Pharmacology models at GSK. Integrating data in clinical studies to enhance decision-making in oncology research and development.

Posted 7/6/2026full-timeWaltham • Massachusetts, North Carolina, Pennsylvania • 🇺🇸 United StatesSenior💰 $151,500 - $252,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in developing and applying Quantitative Systems Pharmacology (QSP) models, with a strong foundation in mathematical and statistical methods for drug research and development. Proficient in translating complex modeling outcomes into actionable insights for project teams, particularly in the oncology therapeutic area.

Highest-signal resume keywords

PhD In Applied MathematicsQuantitative Systems Pharmacology (QSP)Mathematical Modeling And SimulationPK-PD Model DevelopmentStatistical Analysis

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Mathematical MethodsStatistical MethodsModeling And Simulation PackagesData AnalysisMechanistic InterpretationComplex Data InterpretationBiological Suitability AssessmentOncology ExpertiseQSP MethodologiesAnalytical Approaches

Soft Skills

CollaborationCommunicationProblem-Solving

Tools & Technologies

MATLABRJuliaSimBiologyNONMEMWINNONLINSimcypSAS

Industry Keywords

Clinical Study DesignDrug Research And DevelopmentPharmaceutical SciencesSystems BiologyQuantitative Clinical Pharmacology

About the role

Key responsibilities & impact

develop and apply QSP models to guide clinical study designs and mechanistic interpretation of study results
integrate and share data and knowledge in a highly stimulating, collaborative, and multi-disciplinary environment
serve as QSP modeling & simulation point-of-contact in on project teams to solve challenging problems in drug research and development
analyze and interpret complex data sets in the context of disease mechanisms and pathways
explore new QSP opportunities in combining QSP with other analytical approaches
provide both scientific and strategic expertise in oncology therapeutic area
perform scientific rigor and biological suitability assessment of QSP models and methodologies

Requirements

What you’ll need

PhD in Applied Mathematics, Engineering, Pharmaceutical Sciences, Systems Biology, or related disciplines
experience in the application of mathematical and statistical methods
experience working with the theory, principles, statistical aspects of mathematical modeling and simulation
computational experience with one or more modeling and simulation packages or programming languages (e.g., MATLAB, R, Julia, SimBiology, C/C++)
experience working with common tools for quantitative clinical pharmacology (such as NONMEM, R, WINNONLIN, Simcyp, SAS)
experience developing mechanistically-sound PK-PD models
experience translating, condensing, summarizing outcomes of modeling and simulation analyses into information that can be understood by project teams

Benefits

Comp & perks

health care and other insurance benefits (for employee and family)
retirement benefits
paid holidays
vacation
paid caregiver/parental and medical leave