Senior Scientific Director, Oncology

GSK

Senior Scientific Director driving clinical safety strategy and governance for oncology assets at GSK. Leading decision-making processes and ensuring patient safety in clinical and post-marketing settings.

Posted 6/6/2026full-timeMassachusetts, Pennsylvania • 🇺🇸 United StatesSenior💰 $217,800 - $363,000 per yearWebsite

About the role

Key responsibilities & impact

Define and drive the clinical safety and pharmacovigilance strategy for assigned oncology assets in alignment with global business objectives
Lead safety governance activities, ensuring appropriate escalation, communication, and resolution of emerging safety issues
Anticipate, identify, and address safety signals, ensuring effective and timely implementation of risk mitigation strategies
Provide strategic recommendations on benefit-risk profiles to support development and lifecycle management decisions
Exercise expert scientific judgment in the evaluation and interpretation of complex safety data
Lead safety data analyses and signal detection activities, ensuring scientifically robust conclusions and documentation
Guide causality assessments, benefit-risk evaluations, and safety evidence generation across the portfolio
Oversee proactive identification and assessment of safety signals from clinical trials, post-marketing data, and real-world evidence
Develop and implement risk management strategies, including labeling updates, risk minimization measures, and stakeholder communication plans
Lead and influence global, matrixed teams to ensure alignment and execution of safety strategies
Build strong collaborative relationships across clinical, regulatory, medical, and commercial functions
Contribute to due diligence activities, including safety assessments for business development opportunities
Provide strategic oversight and input into regulatory safety documents and responses to Health Authorities

Requirements

What you’ll need

Advanced degree in a relevant scientific or healthcare discipline (e.g., PhD, PharmD, RN/BSN/MSN, NP, RPh, or equivalent)
Significant experience (7+ years) in pharmacovigilance and drug safety within the pharmaceutical or biotech industry
Deep expertise in clinical safety across drug development and post-marketing environments
Demonstrated experience in: Signal detection and evaluation
Benefit-risk assessment and safety decision-making
Risk management strategy development
Strong knowledge of global pharmacovigilance regulations (ICH, GVP, CIOMS)
Experience working in complex, global matrix organizations
Proven ability to influence decisions and lead safety strategy at a program or portfolio level

Benefits

Comp & perks

health care and other insurance benefits (for employee and family)
retirement benefits
paid holidays
vacation
paid caregiver/parental and medical leave

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

pharmacovigilancedrug safetysignal detectionbenefit-risk assessmentrisk management strategy developmentsafety data analysissafety evidence generationcausality assessmentssafety governancerisk mitigation strategies

Soft Skills

leadershipcollaborationcommunicationstrategic thinkinginfluenceproblem-solvingscientific judgmentrelationship buildingdecision-makingorganizational skills

Certifications

PhDPharmDRNBSNMSNNPRPh