Director, Computational Statistics – Human Genetics and Genomics
GSK
CloudPython
Director – Quantitative Systems Pharmacology
GSK
full-time
Posted on:
Location Type: Hybrid
Location: Stevenage • 🇬🇧 United Kingdom
Visit company websiteJob Level
Lead
About the role
- Build and/or guide mathematical model development to understand disease, its progression, and drug action
- Apply mechanistic models of biological, physiological, and pathophysiological processes to evaluate a disease and its pathways
- Develop and/or utilize state-of-the-art mathematical tools to gain insight into causal relationships
- Define and execute a coordinated scientific and technical strategy with demonstrated ability to co-ordinate outputs
- Work in close collaboration with biologists, clinicians, clinical pharmacologists, pharmacometricians, etc.
- Implement best practices, trends, lessons learned from internal and external sources
- Create a collaboration framework with internal and external experts
- Learn and apply emerging modeling and simulation methodologies
- Efficiently interact with line and middle management, staff, and external contacts
- Represent QSP CPQM on various internal advisory boards
- Promote transparency and communicate R&D achievements through publications
Requirements
- PhD, MD, or PharmD with experience in mechanistic modelling and simulation and systems biology with applications in pharmaceutical research and development
- Substantial experience in mechanistic mathematical modeling, inverse problem modeling and simulation, and/or scientific machine learning methodologies
- Strong drive and agility to quickly learn and build knowledge on a drug-disease system
- Demonstrated aptitude for productive collaboration in a multi-discipline team
- Clear evidence of ability to make sound judgement in complex situations
- Experience working with senior stakeholders in a cross functional environment
- Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches
Benefits
- Health insurance
- 401(k) matching
- Flexible work hours
- Paid time off
- Professional development opportunities
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
mechanistic modelingsimulation methodologiesscientific machine learninginverse problem modelingmathematical modelingbiological processesphysiological processespathophysiological processesdrug-disease systemModel-Informed Drug Discovery
Soft skills
collaborationcommunicationjudgmentagilitycoordinationproductivitytransparencyteamworkleadershipinterpersonal skills
Certifications
PhDMDPharmD