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GRAIL

Staff Software Development Engineer – MCED, Lab, Data Technology

GRAIL

Staff Software Development Engineer responsible for leading the design and delivery of complex software systems at GRAIL. Working towards early cancer detection through innovative technologies and methodologies.

Posted 7/22/2026full-timeMenlo Park • California • 🇺🇸 United StatesLeadWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates advanced proficiency in software architecture, programming languages, and cloud-based environments, while providing technical leadership and mentoring to engineering teams. Capable of driving innovation and ensuring compliance with regulatory standards in complex system design and development.

Highest-signal resume keywords
Software ArchitectureTechnical LeadershipCloud-Based EnvironmentsCI/CD PipelinesRegulatory Compliance

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
JavaPythonC#C++JavaScriptTypeScriptAPI DevelopmentDatabase ManagementAgile DevelopmentDevOps Practices
Soft Skills
MentoringCollaborationProblem-SolvingCoachingCommunication
Tools & Technologies
AWSAzureGCPCI/CD ToolsDevOps Tools
Certifications & Qualifications
ISO 27001NISTSOC 2HIPAA
Industry Keywords
Cybersecurity PrinciplesRegulated Medical Device EnvironmentIVDDIVDRFDA 21 CFR

Tech Stack

Tools & technologies
AWSAzureCloudCyber SecurityDistributed SystemsGoogle Cloud PlatformJavaJavaScriptPythonTypeScript

About the role

Key responsibilities & impact
  • Lead the end-to-end design, development, testing, and deployment of highly complex and scalable software solutions.
  • Define and enforce software architecture principles, coding standards, and technical best practices across teams.
  • Serve as a technical authority and provide guidance on complex system design, integrations, and platform-level decisions.
  • Collaborate with product management and business stakeholders to shape technical strategy and translate requirements into solutions.
  • Mentor, coach, and provide technical leadership to engineers at all levels, fostering growth and skill development.
  • Conduct deep technical reviews of designs and implementations to ensure quality, performance, and maintainability.
  • Identify, evaluate, and implement new tools, frameworks, and technologies to improve efficiency and system capability.
  • Troubleshoot and resolve the most challenging technical issues across multiple domains and systems.
  • Contribute to roadmap planning and long-term platform evolution strategies.
  • Promote a culture of engineering excellence, innovation, and continuous improvement.

Requirements

What you’ll need
  • Bachelor’s degree in Computer Science, Software Engineering, or related field; Master’s or PhD preferred.
  • 8–12 years of relevant software development experience with a proven record of technical leadership.
  • Advanced proficiency in multiple programming languages and frameworks (e.g., Java, Python, C#, C++, JavaScript/TypeScript).
  • Deep understanding of software architecture, distributed systems, and cloud-based environments (AWS, Azure, GCP).
  • Demonstrated experience designing and delivering complex, high-scale, and mission-critical systems.
  • Strong background in databases, system integration, security, and API development.
  • Proficiency with CI/CD pipelines, DevOps practices, and agile development methodologies.
  • Demonstrated level of knowledge regarding applicable regulatory standards commensurate with the position's complexity and scope, contributing to organizational regulatory compliance. Minimal applicable standards for this position include:
  • Cybersecurity principles, tools, and control frameworks (e.g. ISO 27001, NIST, SOC 2, HIPAA)
  • Operations within the regulated medical device environment (e.g. IVDD, IVDR, FDA 21 CFR 800 series, FDA 21 CFR Part 11)

Benefits

Comp & perks
  • flexible time-off or vacation
  • a 401(k) retirement plan with employer match
  • medical, dental, and vision coverage
  • carefully selected mindfulness programs