GondolaBio

Executive Director, Translational Medicine

GondolaBio

full-time

Posted on:

Location Type: Hybrid

Location: Palo Alto • California • United States

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Job Level

Lead

About the role

  • Partner with discovery and preclinical teams to identify and prioritize translational biomarkers
  • Translate preclinical findings into clinical biomarker strategies, including pharmacodynamic, target engagement, and disease-relevant endpoints
  • Lead development, qualification, and validation of biomarker assays
  • Oversee assay transfer, validation, and execution at CROs and external laboratories
  • Ensure assays are implemented in CLIA-compliant or equivalent environments when appropriate
  • Partner with Clinical Operations to design sample collection schedules, lab manuals, and logistics workflows
  • Coordinate with clinical sites and vendors to ensure sample integrity and operational feasibility
  • Integrate biomarker data with clinical, PK/PD, and safety datasets to generate decision-ready insights
  • Contribute to clinical protocol design, regulatory documentation, and cross-functional decision-making

Requirements

  • PhD, MD, or equivalent in a relevant discipline
  • 10–15+ years of experience in translational medicine, biomarker sciences, or clinical bioanalysis
  • Experience supporting early clinical development (pre-IND through Phase 1/2)
  • Experience managing biomarker strategies in global clinical studies and working with CROs
  • Strong understanding of biomarker assay platforms and bioanalytical validation principles
  • Experience working in or with CLIA or regulated laboratory environments
  • Experience in neurology or CNS disorders
  • Experience with intrathecal or CNS-targeted therapeutics
  • Familiarity with CSF biomarker workflows or neurophysiological biomarkers (e.g., EEG)
Benefits
  • Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
  • A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
  • An unyielding commitment to always putting patients first.
  • A de-centralized model that enables our program teams to focus on advancing science and helping patients.
  • Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
  • A place where you own the vision – both for your program and your own career path
  • A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
  • Access to learning and development resources to help you get in the best professional shape of your life
  • Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
  • Flexible PTO
  • Rapid career advancement for strong performers
  • Potential ability to work on multiple GondolaBio Pharma programs across multiple therapeutic areas over time
  • Partnerships with leading institutions
  • Commitment to Diversity, Equity & Inclusion
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
biomarker assay developmentbiomarker validationbioanalytical validationclinical protocol designsample collection logisticsdata integrationpharmacodynamicstarget engagementdisease-relevant endpointsCNS-targeted therapeutics
Soft Skills
cross-functional decision-makingcoordinationcommunicationleadershiporganizational skills
Certifications
PhDMD