Senior Director, Clinical Programs

GeneDx

Senior Director of Clinical Programs leading initiatives in rare disease diagnostics and managing a clinical program team at GeneDx.

Posted 5/26/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $267,772 - $305,413 per yearWebsite

About the role

Key responsibilities & impact

Lead high-impact programs that advance GeneDx’s mission in rare disease diagnostics and precision medicine.
Direct program ownership as well as managing a team of clinical program managers.
Drive strategic initiatives within the Clinical Development team, including clinical research programs, medical input on product development, and regulatory support.
Support the design and execution of evidence generation strategies for established clinical programs.
Collaborate with internal partners to design and execute projects aligning with established clinical programs and evidence generation strategy.
Partner with internal and external stakeholders on prospective clinical and translational research efforts.
Oversee the development, review, and submission of scientific manuscripts, abstracts, posters, and other publications aligned with clinical programs.
Acts as a subject matter expert for rare diseases and genomic diagnostics for both internal teams and external stakeholders.
Lead and mentor clinical program managers, including resource allocation, coaching, and performance feedback.

Requirements

What you’ll need

PhD, MD (or equivalent) with board certification by the American Board of Medical Genetics and Genomics (or equivalent) required
10+ years of experience in a clinical laboratory or industry role as a board certified ABMGG fellow required
5+ years of experience in a medical affairs or clinical development role required
5+ years of experience leading research efforts related to molecular diagnostics in rare diseases required
Strong level of clinical genetics knowledge in rare diseases
Strong publication record
Ability to work cross-functionally with other teams and external collaborators to drive strategic initiatives forward
Experience working with rare disease biopharma preferred
Experienced in solving complex problems and negotiating business deals
Excellent written and verbal communication skills
Exceptional presentation and public speaking skills
Ability to work independently and manage time effectively
Detail-oriented with strong organizational skills
Proven experience leading teams and managing cross-functional collaborators to deliver on goals of projects and programs
Proficient in working with databases and Microsoft Office Suite.

Benefits

Comp & perks

Paid Time Off (PTO)
Health, Dental, Vision and Life insurance
401k Retirement Savings Plan
Employee Stock Purchase Plan
Employee Discounts
Voluntary benefits
Programs for parents and parents-to-be

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical researchevidence generation strategiesmolecular diagnosticsgenomic diagnosticsscientific manuscript developmentclinical program managementregulatory supportdata analysisclinical genetics knowledgepublication record

Soft Skills

leadershipmentoringcross-functional collaborationproblem-solvingnegotiationcommunicationpresentation skillsorganizational skillstime managementindependence

Certifications

PhDMDboard certification by the American Board of Medical Genetics and GenomicsABMGG fellow