Clinical Trial Manager – CTM

Exact Sciences

Clinical Trial Manager at Exact Sciences responsible for managing clinical trials and ensuring compliance. Collaborating on operational aspects of studies in a fast-paced environment.

Posted 6/19/2026full-timeMadison • California, Wisconsin • 🇺🇸 United StatesMid-LevelSenior💰 $76,000 - $125,000 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Support the coordination and management of operational aspects of a study including planning, start-up, enrollment and close out activities ensuring that deliverables are completed on time and in compliance with department procedures, applicable regulations and quality standards
Participate in the preparation, review and implementation of study related plans and documents including project timelines, study protocols, informed consent forms (ICFs), recruitment plans, monitoring plans, vendor management plans and other essential clinical study documents
Support planning and management of systems and materials required to support the execution of clinical studies
Maintain tools to manage, monitor and report on study health & operations, project timelines, and study finances to department management
Support study database development by reviewing and contributing to case report form (CRF) design, user acceptance testing (UAT), and CRF completion guideline development
Support sample management activities including planning, sample handling, kit supply management, sample shipping, sample processing, and resulting
Support the identification, selection, start-up and performance monitoring of clinical research sites
Support site contracting and study budget management including facilitation of site contract and budget negotiations, invoice review and approval, accrual management and maintenance of budget tracking tools
Oversee study and site management activities such as, training, data entry & query resolution, TMF maintenance, and ensures compliance with study plans such as the study protocol, monitoring plans, and recruitment plans
Conduct monitoring activities as needed
Assist in the closure of studies including planning & facilitation of database lock, site & IRB/EC closure, statistical analysis and clinical study report development
Support the management and oversight of vendors providing support to clinical studies
Provide proactive communication, coordination, and support to sites and members of the cross-functional study team
Actively participate in various team meetings
Interact with investigators and site staff, vendors, key opinion leaders and consultants
Support ongoing study audit readiness and participate in internal or regulatory authority audits
Provide guidance and support to less experienced team members
Participate or may facilitate department or project initiatives under the direction of management or a lead clinical trial manager
Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork
Support and comply with the company’s Quality Management System policies and procedures
Maintain regular and reliable attendance
Ability to act with an inclusion mindset and model these behaviors for the organization
Ability to work designated schedule
Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day
Ability to work on a computer and phone simultaneously
Ability to travel 10% of working time away from work location, may include overnight/weekend travel
Ability to attend off-site meetings and conferences as needed

Requirements

What you’ll need

Bachelor’s Degree in Life Sciences or field as outlined in the essential duties
3+ years of experience in clinical research
Clinical monitoring experience or oversight including data review, query resolution, protocol deviation identification/tracking/trending, site initiation, site maintenance, and site closeout visits
Experience writing, reviewing and editing protocols
Knowledge of applicable quality standards (e.g. Good Clinical Practices (ICH/GCP), ISO 20916) and applicable local and national regulations governing clinical research
Proficiency in Microsoft Office programs, such as: Word, Excel, PowerPoint, Outlook, Teams, SharePoint, or MS Project
Demonstrated ability to perform the essential duties of the position with or without accommodation
Authorization to work in the United States without sponsorship

Benefits

Comp & perks

Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
Retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical researchclinical monitoringdata reviewquery resolutionprotocol writingprotocol editingcase report form designuser acceptance testingbudget managementsample management

Soft Skills

communicationcoordinationteamworkleadershipproblem-solvingattention to detailorganizational skillsproactive mindsetinclusion mindsetaccountability