Senior Principal Medical Development Director, Breast Portfolio

Exact Sciences

Sr. Principal Medical Development Director at Exact Sciences, leading oncology strategies and collaborations for breast cancer diagnostics.

Posted 5/15/2026full-timeSan Diego • California, Wisconsin • 🇺🇸 United StatesSenior💰 $300,000 - $392,000 per yearWebsite

About the role

Key responsibilities & impact

Develop the overall vision and strategy for one or more specific Precision Oncology products
Identify opportunities to expand indications for existing products and new products within the biotech/pharma space
Collaborate with cross-functional team members to participate in and provide medical expertise to the formulation of commercialization strategy
Participate as the medical monitor on study teams and lead the development and implementation of clinical protocols
Engage with medical leaders within oncology to facilitate their understanding of the scientific validity of Exact PO products
Accountable for scientific presentations and publications generated as a result of PO product development collaborations
Provide oncology expertise and clinical insight for cross-functional teams throughout the lifecycle of practice-changing tests and services
Engage with colleagues in the medical organization to drive continuous improvement of team leadership practices
Create an innovative and proactive approach to identify biopharma partners for new product opportunities

Requirements

What you’ll need

M.D., D.O., in a related field as outlined in the essential duties
Completion of fellowship training or equivalent in medical oncology
Demonstrated expertise in molecular oncology
Demonstrated ability to lead cross-functional internal and external teams of professionals focused on complex, multi-faceted projects
Familiarity with laboratory analytical process development and biostatistics
Demonstrated ability to perform the essential duties of the position with or without accommodation
Authorization to work in the United States without sponsorship
2+ years of experience in healthcare (preferred)
Experience in oncology within the pharmaceutical or biotech industry with an emphasis on clinical or translational research (preferred)
Experience working with various drug classes used in the management of breast cancer patients (preferred)
Experience in the development of new oncology therapeutics and molecular diagnostics (preferred)
Strong knowledge of FDA and Ex-U.S. regulatory documentation and processes (preferred)

Benefits

Comp & perks

paid time off (including days for vacation, holidays, volunteering, and personal time)
paid leave for parents and caregivers
a retirement savings plan
wellness support
health benefits including medical, prescription drug, dental, and vision coverage

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Hard Skills & Tools

molecular oncologyclinical protocolsbiostatisticsoncology therapeuticsmolecular diagnosticsFDA regulatory documentationEx-U.S. regulatory processeslaboratory analytical process development

Soft Skills

leadershipcollaborationcommunicationinnovationstrategic thinkingteam managementmedical expertise

Certifications

M.D.D.O.fellowship training in medical oncology