Principal Automation, MES Engineer

Evotec

Principal Automation & MES Engineer responsible for design and optimization of MES solutions in a regulated environment. Leading projects and collaborating with various operational teams in manufacturing.

Posted 7/22/2026full-timeRedmond • Washington • 🇺🇸 United StatesLead💰 $140,000 - $170,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in the design, implementation, and optimization of Manufacturing Execution Systems (MES) while ensuring compliance with GMP, FDA, and GAMP5 standards. Proven ability to lead complex technical projects and enhance manufacturing efficiency through effective system integration and data management.

Highest-signal resume keywords

Manufacturing Execution Systems (MES)Process Automation PlatformsGMP ComplianceFDA RegulationsSystem Integration

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Manufacturing Execution Systems (MES)Process AutomationSystem IntegrationData AnalyticsTechnical Project LeadershipGMP ComplianceFDA RegulationsGAMP521 CFR Part 11SDLC Methodologies

Soft Skills

Analytical SkillsTroubleshootingOrganizational SkillsCommunication Skills

Tools & Technologies

DeltaVSCADAPLCHMIPAS-XSyncadePharmaSuiteOpcenterSiemensAllen-Bradley

Industry Keywords

Pharmaceutical ManufacturingBiotechnologyMedical Device ManufacturingRegulated Environments

Tech Stack

Tools & technologies

ERPSDLC

About the role

Key responsibilities & impact

The Principal Automation & MES Engineer is responsible for the design, implementation, optimization, and lifecycle management of Manufacturing Execution Systems (MES)
Lead the design, configuration, deployment, and continuous improvement of MES solutions to support manufacturing operations, electronic batch execution, data integrity, and operational efficiency
Support integration of MES platforms with enterprise and site systems including ERP, LIMS, historians, SCADA/DCS, CMMS, and data analytics platforms
Define and maintain MES governance, standards, lifecycle management practices, and system roadmaps aligned with business objectives
Participate in enterprise digital manufacturing initiatives
Provide technical leadership for automation and process control systems including DeltaV, SCADA, PLC, HMI, and related manufacturing control platforms
Ensure manufacturing systems remain compliant with GMP, FDA, GAMP5, and 21 CFR Part 11 requirements
Lead or contribute to capital projects, system implementations, upgrades, migrations, and site expansion initiatives
Identify opportunities to improve manufacturing efficiency, data visibility, system reliability, and process robustness

Requirements

What you’ll need

Bachelor’s or Master’s degree in Engineering, Computer Science, Biotechnology, Automation, or related technical discipline
10+ years of experience in pharmaceutical, biotechnology, medical device, or other regulated manufacturing environments
Strong experience with Manufacturing Execution Systems (MES) platforms such as PAS-X, Syncade, PharmaSuite, Opcenter, or equivalent
Experience with process automation platforms such as DeltaV, Siemens, Allen-Bradley, Wonderware, Ignition, or related technologies
Demonstrated experience supporting validated manufacturing systems within GMP-regulated environments
Strong understanding of FDA regulations, GAMP5, SDLC methodologies, and 21 CFR Part 11 compliance requirements
Proven experience leading complex technical projects and cross-functional engineering initiatives
Experience with system integration, manufacturing data flows, and enterprise application connectivity
Strong analytical, troubleshooting, organizational, and communication skills
Ability to work effectively across global teams, manufacturing sites, and external partners.

Benefits

Comp & perks

comprehensive benefits to include Medical, Dental and Vision
short-term and long-term disability
company paid basic life insurance
401k company match
flexible work
generous paid time off and paid holiday
wellness and transportation benefits