Director/Senior Director, Analytical Methods – Methods4Insight

Eli Lilly and Company

Director/Senior Director developing and deploying analytical methods for drug discovery at Lilly. Collaborating with teams to ensure integration of analytical solutions across the discovery ecosystem.

Posted 8/2/2026full-timeSan Francisco • California, Colorado • 🇺🇸 United StatesSenior💰 $193,500 - $338,800 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in developing and deploying analytical methods in drug discovery, with strong programming skills in Python and R. Proven ability to mentor junior scientists and communicate complex concepts effectively across diverse audiences.

Highest-signal resume keywords

Analytical Method DevelopmentPython ProgrammingPeer-Reviewed PublicationsMentoring Junior ScientistsData-Driven Decision Making

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Analytical MethodsCheminformaticsComputational BiologyBiophysicsApplied MathematicsStatisticsScientific ComputingMethod ValidationExperimental DesignSoftware Engineering Practices

Soft Skills

Effective CommunicationMentoringCollaborationScientific RigorContinuous Improvement

Tools & Technologies

APIsAI Decision-Making ToolsData Integration WorkflowsResearch Code Deployment

Industry Keywords

Drug DiscoveryLife SciencesScientific OutcomesAnalytical LiteracyExperimental Outcomes

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Serve as the subject matter expert in your analytical domain, staying current on innovative methods and making informed recommendations about adoption, adaptation, or development of novel approaches
Develop and deploy cutting-edge analytical methods tailored to Lilly's discovery challenges, building workflows that integrate multiple approaches (e.g., physics-based and data-driven) to harness complementary strengths
Work alongside discovery project teams to translate complex scientific questions into tractable analytical problems, driving analyses that directly inform compound prioritization, design recommendations, and mechanism of action hypotheses
Collaborate with Architecture4Insight to deploy analytical methods as accessible tools and agent-ready capabilities with well-defined APIs for autonomous AI decision-making
Identify strategic data gaps in your domain and partner with Scale4Insight to design targeted experiments that generate data in high-value areas
Establish best practices for method validation, including prospective testing against experimental outcomes, and demonstrate impact through tracked metrics: decisions influenced, hypotheses generated, and timelines accelerated
Collaborate across all Data Foundry pillars and with Frontier AI to ensure analytical capabilities are fully integrated into the broader discovery ecosystem
Publish peer-reviewed research, present at scientific conferences, and build analytical literacy across the organization
Mentor junior computational scientists and contribute to a culture of scientific rigor, reproducibility, and continuous improvement.

Requirements

What you’ll need

MS/Ph.D. in Cheminformatics, Computational Biology, Biophysics, Applied Mathematics, Computer Science, Statistics, or a related quantitative field
6+ years of experience developing and applying analytical methods in drug discovery or related life sciences fields
Deep expertise in at least one analytical domain with demonstrated impact on scientific outcomes
Strong programming skills in Python, R, or similar scientific computing languages
Publications in peer-reviewed journals demonstrating contributions to your analytical domain
Ability to explain complex analytical concepts clearly to non-computational scientists
Track record of deploying analytical methods that influenced real scientific decisions or discoveries
Breadth across multiple analytical approaches, with experience both developing novel methods and adopting external approaches
Familiarity with software engineering practices and deploying research code in production environments
Experience mentoring junior scientists or managing interns/postdocs
Ability to communicate effectively across scientific, technical, and executive audiences
Passion for mentoring and empowering others.

Benefits

Comp & perks

eligibility to participate in a company-sponsored 401(k)
pension
vacation benefits
eligibility for medical, dental, vision and prescription drug benefits
flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
life insurance and death benefits
certain time off and leave of absence benefits
well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)