Disc Medicine

Research Scientist

• Provide scientific leadership in the planning, execution, and data interpretation across multiple biologics discovery programs.
• Lead protein engineering strategies for various antigens and biologics (antibodies and multi-specifics) using experimental, computational and structural biology tools
• Design and oversee the protein production and detailed characterization processes to support projects across the Innovation portfolio
• Drive early-stage developability assessment workflows of biologics
• Support mechanisms of action studies through assay development
• Support the selection of lead molecules to advance pipeline programs.
• Critically evaluate scientific literature, synthesize novel hypotheses and design and integrate rigorous experimental strategies to test them.
• Communicate project progress and key findings effectively in cross-functional meetings, ensuring alignment with timelines in a fast-paced, dynamic environment.
• Foster a collaborative and accountable team culture, with a strong emphasis on scientific excellence and continuous improvement.

Principal Scientist, Protein Production – Engineering

Medical writer

• Partner and collaborate with clinical and regulatory team members in the preparation of clinical protocols and regulatory documents; participate in study results interpretations and manage the document review/approval process to capture comments and resolve conflicts, including running round-table meetings.
• Communicate and coordinate with line-function team members to gather, organize, and compile information towards the development and planning of writing scientific, clinical, and regulatory documents; communicate deliverables needed, writing process and timelines, and hold team members accountable to agreed-upon dates for deliverables.
• Contribute to timeline planning for regulatory and clinical documents authored by Medical Writing.
• Contribute to preparing manuscripts, conference publications, and slides on research discovery results to support Disc publication strategy.
• Perform QC review as Medical Writing line-function representative and for documents written by other Medical Writing team members.
• Ensure applicable guidelines and regulations are followed in the scientific and clinical writing deliverables, including but not limited to the International Conference on Harmonization (ICH), electronic Common Technical Documents (eCTD) guidelines, content, and templates, as well as document-appropriate QC.
• Verify and share literature references to online library, gather and post literature for submissions, search, and order articles as needed.
• Assist with template modification or creation.
• Stay up to date on current industry practices, compliances, regulations, and company standard operating procedures and policies; assist with writing Medical Writing work instructions, guides, and policies.

Medical Writer

Human Resources

• As a strategic leader, directly contribute to corporate success and to strategic planning by developing people-focused solutions for your client groups
• As a member of the Human Resources Leadership Team, ensure that your clients’ people plans are aligned with enterprise HR strategy in support of Disc Medicine’s business objectives
• Develop effective communication and relationships with leaders in client groups; ensure they are empowered with critical talent information and metrics needed to drive the best business decisions and maintain strong employee engagement and the highest ethical standards
• Through active coaching and mentoring, support the organization in continuing to strengthen team performance and excellence in leadership
• Create and support an environment where trust, transparency, credibility, and integrity are recognized as key factors in building long-term positive relationships between the organization, its employees, patients, and shareholders
• Co-lead a community of practice to bring fit-for-purpose policies, programs and practices into a “field ready” state for the entire Company

Senior Director, Human Resources Business Partner – R&D

General

• Identify, develop and maintain strong relationships with KOLs, academic institutions, community centers, and HCPs in relevant areas of focus.
• Engage in meaningful peer-to-peer exchanges with the appropriate therapeutic area community (e.g., hematologists, dermatologists, hepatologists, rare disease community).
• Serve as a scientific expert and resource, providing accurate support to internal and external stakeholders and timely information about Disc’ clinical data, ongoing research and programs.
• Provide internal stakeholders with feedback and actionable insights from interactions and discussions with KOLs and HCPs.
• Assist with company-sponsored trials, investigator-initiated trials (IITs) or research collaborations.
• Deliver scientific presentations and trainings to internal and external stakeholders.
• Assist with organizing regional advisory boards as applicable, and presenting at advisory board meetings within your territory.
• Build a trustful and collaborative working relationship with cross-functional colleagues.
• Focus on delivering results and demonstrate ownership in key medical projects.
• Adhere to all relevant compliance and regulatory guidelines, ensuring all activities are conducted ethically and within legal boundaries.

Medical Science Liaison, Associate

• Characterize biologic therapeutics using standard analytical extended techniques to explore relationships between structure and function.
• Oversee development of standard protein analysis methods through external vendors and guide transfer analytical methods to separate analytical and QC testing facilities.
• Develop analytical techniques to measure product and process impurities.
• Strengthen relationships with external CDMO partners to establish and manage appropriate scopes of work, and to ensure all activities are within program expectations.
• Provide oversight into external testing facilities for non-GMP and GMP testing.
• Lead method performance investigations, troubleshooting, and laboratory investigations.
• Working and up-to-date knowledge of ICH guidelines and other regulatory guidance.
• Author, review and edit SOPs, protocols, reports, and quality related documentation for internal and external stakeholders.
• Provide authorship and review for regulatory documents for multiple countries.
• Collaborate cross-functionally across multi-disciplinary teams including Analytical Development, Process Development, Drug Product Development, Regulatory, Quality Assurance, Supply Chain, and others.

Principal Scientist, Protein Production – Engineering

Medical Writer

Senior Director, Human Resources Business Partner – R&D

Medical Science Liaison, Associate

Principal Scientist – Analytical Development, Clinical Quality Control