End User Computing Engineer

Definium Therapeutics

End User Computing Engineer providing IT support for remote staff at Definium Therapeutics. Responsible for hardware/software issues and managing IT service requests in a regulated environment.

Posted 5/28/2026full-timeSan Diego • California • 🇺🇸 United StatesJuniorMid-Level💰 $100,932 - $123,380 per yearWebsite

Tech Stack

Tools & technologies

iOSITSMMacOS

About the role

Key responsibilities & impact

Provide operational support for remote staff. This will include hardware and software issues
Create, update, triage, and close support tickets in the Definium ITSM to ensure a thorough documentation of requests and incidents, end-user communication, root cause analysis and resolution
IT lead for all new and departing employee responsibilities. Ensure compliance with all on-boarding and off-boarding policies and procedures
Coordinate the hardware lifecycle for remote employees from procurement, configuration, collection, and retirement
Provide primary/secondary system administration to IT systems
Work closely with IT MSPs and professional service providers
Assist in identifying, evaluating, justifying, and deploying, new products, technologies, systems, services, and workflows
Independently perform actions under departmental change control procedures with minimal oversight or assistance
Ensure compliance for technology projects and processes including Sarbanes Oxley (SOX), 21 CFR Part 11, cGxP, and GDPR
Author and review standard operating procedures and knowledge-based articles for the maintenance and operation of software applications
Ensure that best practices for the service and support of technology products are documented and followed
Stay up to date on industry trends and best practices

Requirements

What you’ll need

Minimum bachelor’s degree or equivalent work experience
2+ years of Tier I operational support experience, preferably within a regulated life sciences environment that has a remote or hybrid workforce
2+ years supporting macOS and Windows laptops via MDM
2+ years supporting Identity platforms [OKTA or Entra/AzureAD]
2+ years supporting SaaS applications
Experience administering Co-Pilot, M365, SharePoint, Powershell, Cisco Umbrella, CrowdStrike, CheckPoint, M365, Slack, Zoom, DocuSign, FreshService, Intune, Kandji, Apple Business Manager, Adobe, and OKTA
Strong verbal and written communication skills
Excellent vendor management and negotiation skills
Strong remote triaging skills
Strong experience managing SharePoint sites and M365 permissions
SOX and/or 21 CFR Part 11 experience
Experience supporting multiple operating systems (Windows 11, iOS, and MacOS)
ITIL certification preferred

Benefits

Comp & perks

100% paid health benefits including Medical, Dental and Vision for you and your dependents
401(k) program with company match and vesting after the turn of the first month after your start date
Flexible time off
Generous parental leave and some fun fringe perks!

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

operational supportsystem administrationroot cause analysishardware lifecycle managementremote supportMDMSaaS applicationsvendor managementtriagingSharePoint management

Soft Skills

verbal communicationwritten communicationnegotiation skillsremote triaging skills

Certifications

ITIL certification