Deep Genomics

Research Scientist

• Establish and lead the in vivo pharmacology function to advance RNA editing therapeutics.
• Lead all in vivo work from design, model development, execution, analysis and interpretation.
• Design, execute and interpret translational studies for genetic medicines in mice and NHP.
• Collaborate closely with therapeutic program teams on relevant in vitro models and development of translational assays.
• Collaborate closely with the target discovery team on availability, feasibility and predictive power of pre-clinical models for new targets.
• Provide strategic leadership on the clinical development path including regulatory filings and biomarker development.
• Plan and contribute to writing regulatory submissions (e.g., IND) and biomarker strategies in collaboration with internal leaders, external consultants and KOLs.
• Lead studies with external research organizations and act as a connector between internal groups.
• Analyze, interpret and present data to scientists and management in internal and external venues and publish in peer-reviewed journals as appropriate.
• Mentor and potentially manage direct reports; demonstrate leadership and cross-functional influence.

Principal Scientist, In Vivo Pharmacology