Senior Director, Immunology and Translation

CSL

Senior Director overseeing immunology research and development at CSL Behring. Leading scientific strategy and asset progression while collaborating with cross-functional teams.

Posted 6/9/2026full-timeWaltham • Massachusetts • 🇺🇸 United StatesSenior💰 $302,000 - $350,000 per yearWebsite

About the role

Key responsibilities & impact

Serve as the primary scientific expert and internal champion for one or more immunology disease areas
Translate deep mechanistic understanding of immune pathology into actionable therapeutic hypotheses and target identification strategies
Maintain a current and comprehensive view of the competitive landscape, emerging science, and unmet medical need across assigned disease areas
Represent CSL Behring at key scientific conferences, advisory boards, and KOL meetings; build and leverage a broad external network of thought leaders, clinical investigators, and academic collaborators
Drive end-to-end asset progression from ideation through first-in-disease designation, integrating scientific rationale, translational endpoints, patient population selection, and regulatory strategy
Lead or co-lead target and asset evaluation activities including preclinical data package reviews, mechanism-of-action assessments, and translational feasibility analyses
Provide scientific input to IND-enabling studies, proof-of-concept study designs, and Phase 1/1b protocol development
Collaborate with the discovery and translational teams to define disease-relevant biomarkers, pharmacodynamic readouts, and patient stratification strategies for early clinical programs
Actively contribute to R&D programs as a subject matter expert and provide guidance for the clinical development pathway
Partner with Business Development to assess in-licensing, partnering, and acquisition opportunities within the immunology space, providing scientific due diligence leadership
Contribute to Target Product Profiles (TPPs), integrated development plans, and portfolio reviews
Provide disease area expertise to regulatory submissions, clinical study reports, and scientific communications
Work collaboratively with Medical Affairs, Clinical Operations, and translational colleagues to align development strategies.

Requirements

What you’ll need

MD, DO, or PhD in Immunology, or a closely related discipline
12+ years of experience in drug development within a biotech, pharmaceutical, or academic environment
Demonstrated experience in preclinical to first-in-disease (or equivalent early clinical milestone) in immunology
Deep scientific expertise in the immunological mechanisms underpinning autoimmune and inflammatory diseases
Established and active network in drug development with recognized relationships across rheumatology, neuroimmunology, and/or dermatology communities
Proven track record in evaluating preclinical and clinical assets, including target assessment, data package review, and go/no-go decision-making
Strong ability to synthesize complex scientific data and communicate strategy clearly to diverse audiences including senior leadership.

Benefits

Comp & perks

Health insurance
Professional development opportunities
Flexible work arrangements
Bonuses
Stock options

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

immunologydrug developmentpreclinical studiesclinical study designbiomarkerspharmacodynamicsregulatory strategytarget identificationmechanism-of-action assessmenttranslational feasibility analysis

Soft Skills

scientific communicationnetworkingcollaborationleadershipstrategic thinkingdata synthesisguidancerelationship buildingproblem-solvingdecision-making

Certifications

MDDOPhD