Principal Programmer, Data Oversight & Standards

CSL

Principal Programmer overseeing clinical data build, programming, and vendor deliverables to ensure compliance and quality standards. Driving integration and automation in the data lifecycle at CSL Behring.

Posted 5/6/2026full-timeWaltham • Massachusetts, Pennsylvania • 🇺🇸 United StatesLead💰 $170,000 - $201,000 per yearWebsite

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Provides leadership and oversight for clinical data build, programming, and vendor deliverables.
Drives governance, review, and validation processes.
Leads the implementation of CDASH and SDTM standards.
Oversees scalable validation frameworks and data quality controls.
Ensures effective integration of internal and external data into platforms such as the CSL Clinical Data Warehouse.
Ensures submission readiness of clinical data by establishing robust quality control frameworks.

Requirements

What you’ll need

Education Degree (BSc/MSc/Diploma) in Computer Science, Mathematics/Statistics, or related area with relevant experience.
At least 7 years of relevant experience (either clinical programming and/or statistical programming, within the CRO/pharmaceutical environment).
Significant experience with demonstrated leadership or oversight responsibilities and a strong understanding of the end-to-end clinical data lifecycle.
Proven expertise in CDISC standards (CDASH, SDTM, ADaM) and their practical application across studies.
Experience with EDC and/or Clinical Data Warehouse platforms.
Proficiency in SAS programming, with working knowledge of Python, R, or similar languages preferred.
Demonstrated experience in establishing or applying data quality frameworks, validation processes, and governance models in a clinical data environment.
Proven ability to manage priorities, timelines, and team deliverables in a fast-paced environment.

Benefits

Comp & perks

Health insurance
401(k) matching
Flexible work hours
Paid time off
Professional development opportunities

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

SAS programmingPythonRCDASHSDTMADaMclinical programmingstatistical programmingdata quality frameworksvalidation processes

Soft Skills

leadershipoversightgovernancecommunicationprioritizationtime managementteam managementorganizational skillsproblem-solvingattention to detail