Executive Director, Molecular Design Technology

Bristol Myers Squibb

Executive Director, Molecular Design Technology at Bristol Myers Squibb focusing on AI-driven drug discovery processes and technology strategy. Collaborating with scientific leaders for integrated design ecosystem development.

Posted 7/6/2026full-timeCambridge Crossing • California, Massachusetts, New Jersey • 🇺🇸 United StatesLead💰 $262,480 - $318,064 per yearWebsite

About the role

Key responsibilities & impact

Own the end-to-end technology strategy and roadmap for molecular design and optimization across modalities (small molecule, biologics, and emerging).
Align priorities and drive delivery in close partnership with Discovery Biology, Medicinal Chemistry, Computational Sciences, and lab leadership.
Select and scale core platforms and tools for structure-based design, modeling & simulation, AI/generative design, and design-workflow visualization.
Architect and deliver an integrated design ecosystem (interoperable tools, datasets, and workflows) to reduce fragmentation and improve usability.
Deliver measurable outcomes (e.g., DMTA cycle-time reduction; closed-loop optimization) through AI/ML, generative, and agentic capabilities.
Own compound and entity registration systems and workflows, partnering with the R&D Data organization on the registered-entity data product.
Ensure operational excellence (reliability, performance, support, and governance) for design platforms and integrated applications.
Connect upstream Research with downstream Development (e.g., CMC and Manufacturing IT) so Development learnings flow back into design decisions.
Build and lead a high-performing organization (talent, culture, performance) and manage external partnerships (vendors, startups, academic collaborators).

Requirements

What you’ll need

Ph.D. in Chemistry, Computational Chemistry, Structural Biology, Bioinformatics, or related field
15+ years of experience in drug discovery, with:
Deep experience in molecular design (small and/or large molecule)
10+ years operating at the intersection of science and technology/IT
Proven track record of leading technology-enabled transformation in a pharmaceutical or biotech R&D environment
Demonstrated experience implementing or scaling:
Molecular modeling platforms
AI/ML-driven drug design capabilities
Integrated scientific data environments
Strong understanding of end-to-end drug discovery workflows, particularly within design and optimization phases
Experience deploying GenAI and agentic capabilities into scientist workflows, and driving DMTA cycle-time reduction or comparable closed-loop optimization
Experience operating at Director/Senior Director level or above, with readiness for Executive Director scope

Benefits

Comp & perks

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

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Applicant Tracking System Keywords

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Hard Skills & Tools

Molecular Modeling PlatformsDrug Discovery WorkflowsStructure-Based DesignModeling & SimulationGenerative DesignDesign-Workflow VisualizationClosed-Loop OptimizationDMTA Cycle-Time ReductionAgentic CapabilitiesComputational Sciences

Soft Skills

LeadershipCollaborationStrategic AlignmentOperational ExcellencePerformance Management