Senior Principal Scientist, Neuroscience, Clinical Biomarker, Late Phases, Translational Medicine

Bristol Myers Squibb

Senior Principal Scientist leading neuroscience clinical biomarker research at Bristol Myers Squibb. Designing and implementing translational plans for late-stage clinical development across therapeutic areas.

Posted 6/2/2026full-timeCalifornia, Massachusetts, New Jersey • 🇺🇸 United StatesSenior💰 $160,060 - $223,036 per yearWebsite

About the role

Key responsibilities & impact

Designs and implements program-specific late development biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable
Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs
Prepares and delivers internal and external translational/biomarker presentations
Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed
Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology
Works with TM laboratory scientists and academic TLs to address nonclinical translational questions
Participates in post-hoc biomarker analysis and publication efforts
Supports regulatory submissions and regulatory interactions as needed

Requirements

What you’ll need

PhD or MD/PhD in neuroscience with 7+ years of translational medicine experience
5+ years of late stage clinical biomarker experience in biotech/pharma
Recognized expertise in translational biomarkers in neuroscience space
Experience in late-stage drug development and activities required for and related to clinical trial initiation, maintenance and completion
Strong verbal and written communication skills
Experience in interacting with CROs and TLs to manage projects and timelines
Proven scientific/leadership expertise (working in teams, mentoring people, managing projects)
Accountable for timelines and deliverables
Prioritizes risks and implements contingency plans
Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested
Recognizes cross-functional issues and communicates within the larger organization.
Provides expert guidance to multi-disciplinary teams and senior management.
Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.
Ability to prioritize and manage time efficiently
Accurate and detailed record keeping
Excellent organizational skills

Benefits

Comp & perks

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

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Hard Skills & Tools

biomarker developmentclinical trial managementdata analysisassay validationtranslational medicineproject managementregulatory submissionsscientific literature evaluationpresentation skillscross-functional collaboration

Soft Skills

strong communication skillsleadership expertisementoringaccountabilityrisk prioritizationtime managementorganizational skillsdetail-orientedteam collaborationproblem-solving

Certifications

PhD in neuroscienceMD/PhD