Principal Scientist, Analytical Science and Technology, Cell Therapy

Bristol Myers Squibb

. The Principal Scientist is a highly experienced subject matter expert responsible for leading method optimization, transfer, and validation in support of Cell Therapy analytical portfolio.

Posted 5/22/2026full-timeSeattle • Massachusetts, Washington • 🇺🇸 United StatesLead💰 $124,590 - $155,211 per yearWebsite

About the role

Key responsibilities & impact

The Principal Scientist is a highly experienced subject matter expert responsible for leading method optimization, transfer, and validation in support of Cell Therapy analytical portfolio.
Conceptualize and lead complex projects, provides strategic scientific and technical input to the programs and projects.
Apply technical knowledge, regulatory requirements, and scientific principles to independently perform complex troubleshooting and problem solving.
Balance deep hands-on laboratory involvement with cross-functional leadership, mentoring, and external scientific engagement.
Represent the department in product review boards, regulatory inspections (internal and external audits).
Own and author relevant analytical sections of regulatory submission and responses to health authority questions and requests.

Requirements

What you’ll need

Bachelor’s/Master’s degree preferably in (bioanalytical) science. Advanced degree preferred.
10+ years of relevant experience in regulated cellular therapy or gene therapy, or an equivalent combination of education and experience.
Expert scientific knowledge with a broad range of bioanalytical techniques (cell-based assays, ELISA, qPCR, flow cytometry).
Strong scientific background and expertise with various analytical methodologies including those related to lentiviral, AAV vectors and other gene delivery platforms.
Demonstrated advanced technical writing skills.
Advanced strategic thinking and problem-solving ability/mentality, technically adept and logical.
Ability to work independently in a fast-paced matrix environment, meet deadlines, and prioritize work from multiple projects.
Track record of scientific productivity as evidenced by publications, presentations, or equivalent internal contributions.
Advanced ability to communicate and collaborate effectively with peers, senior management and cross-functional peers about task status, roadblocks and needs, locally and globally.
Strong hands-on laboratory skill set, including execution, and interpretation of complex, high-impact scientific, multi-dimensional data in support of commercial QC analytical methods.
Ability to travel to support projects as needed.

Benefits

Comp & perks

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays).
Optional holidays.
Additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

bioanalytical techniquescell-based assaysELISAqPCRflow cytometryanalytical methodologieslentiviral vectorsAAV vectorsgene delivery platformstechnical writing

Soft Skills

strategic thinkingproblem-solvingindependent worktime managementcommunicationcollaborationmentoringleadershiptroubleshootingscientific engagement

Certifications

Bachelor’s degreeMaster’s degree