Director, Degrader Chemistry

BioNTech SE

Director advancing protein degraders, molecular glues, and ADC chemistry at BioNTech, a biotechnology company developing innovative medicines. Collaborating across R&D, CMC, CROs, and CDMOs to support preclinical development and GMP manufacturing.

Posted 8/10/2026full-timeCambridge • Massachusetts • 🇺🇸 United StatesLead💰 $168,100 - $268,700 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in protein degraders and molecular glues, with a strong background in organic chemistry and drug discovery. Proven ability to collaborate cross-functionally and prepare preclinical documents for IND filing.

Highest-signal resume keywords

Ph.D. In Organic ChemistryProtein Degraders ExpertiseMolecular Glues ExpertiseDrug Discovery ExperienceGMP Manufacturing Coordination

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Protein Degrader DesignMolecular Glue SynthesisPreclinical Document PreparationProcess DevelopmentLinker ChemistryConjugation ChemistryADC Payload KnowledgeCreative ThinkingPublication RecordPresentation Skills

Soft Skills

Highly OrganizedProactive MentalityTeam-Centered CollaborationExcellent Interpersonal SkillsNetworking SkillsCommunication Skills

Industry Keywords

ADC ResearchCMC Team CollaborationIND FilingCRO CollaborationCDMO Collaboration

About the role

Key responsibilities & impact

Participate in ADC research and development programs by providing chemistry know-how and expertise in protein degraders, molecular glues, payloads, and linkers
Design and synthesize protein degraders and molecular glues
Coordinate and collaborate with the CMC team supporting process development and GMP manufacturing
Prepare preclinical documents for IND filing
Work cross-functionally within the R&D organization
Collaborate with outside partners, CROs, and CDMOs

Requirements

What you’ll need

Ph.D. or M.S. in organic chemistry or a related discipline
8 plus years of industry experience in drug discovery and development
Strong experience in protein degraders and molecular glues
Proven track record of creative thinking and consistent delivery demonstrated by publication/presentation records
Highly organized with a proactive mentality
Ability to thrive in a team-centered and collaborative environment
Excellent interpersonal, networking, and communication skills
Preferred: experience in ADC payload, linker, and conjugation chemistry
Preferred: experience in ADC manufacturing process development
Background check conducted as part of the recruitment process

Benefits

Comp & perks

Medical, Dental and Vision Insurance
Life, AD&D, Critical Illness Insurance
Pre-tax HSA & FSA, DCRA Spending Accounts
Employee Assistance & Concierge Program (EAP) available 24/7
Parental and Childbirth Leave & Family Planning Assistance
Sitterstream: Virtual Tutoring & Childcare Membership
Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown
401(K) Plan with Company Match
Tuition Reimbursement & Student Loan Assistance Programs
Wellbeing Incentive Platforms & Incentives
Professional Development Programs
Commuting Allowance and subsidized parking
Discounted Home, Auto & Pet Insurance
Annual bonus
Equity