Executive Director – Medical Clinical Operations

BioNTech SE

Executive Director of Medical Operations at BioNTech managing external research portfolio. Collaborates with teams to drive innovation and ensures compliance in clinical research.

Posted 4/23/2026full-timeBerkeley Heights • New Jersey • 🇺🇸 United StatesLead💰 $245,000 - $392,000 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Lead the strategy, prioritization, and management of BioNTech’s global external research portfolio across IIS, CRS, Phase IV/PASS programs.
Collaborate with Medical Affairs, Clinical Development, Market Access, and Commercial teams to define and execute a multi-year cross-indication external research strategy.
Establish global standards for external research processes and governance while driving harmonization across regions.
Ensure efficient and compliant execution of external research programs by leading cross-functional project teams.
Develop robust financial frameworks for forecasting, milestone payments, and resource utilization aligned with corporate priorities.
Drive strategic initiatives such as improving governance models and building data/RWE platforms.

Requirements

What you’ll need

Advanced degree in life sciences or health-related disciplines (e.g., MD, PharmD, PhD) preferred; bachelor’s degree with extensive relevant experience also considered.
Extensive experience (12–15+ years) in clinical research or Medical Affairs within biopharma or academic settings.
Proven track record in managing large-scale multinational study portfolios including IIS and RWE programs.
Strong leadership skills in matrix organizations; ability to influence without direct line authority.
Deep knowledge of ICH GCP guidelines, regulatory standards, and ethical compliance requirements.
Exceptional negotiation abilities with academic institutions and vendors at a global level.
Strategic mindset paired with financial acumen for budget ownership and scenario analysis.

Benefits

Comp & perks

Medical, Dental and Vision Insurance
Life, AD&D, Critical Illness Insurance
Pre-tax HSA & FSA, DCRA Spending Accounts
Employee Assistance & Concierge Program (EAP) available 24/7
Parental and Childbirth Leave & Family Planning Assistance
Sitterstream: Virtual Tutoring & Childcare Membership
Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
401(K) Plan with Company Match
Tuition Reimbursement & Student Loan Assistance Programs
Wellbeing Incentive Platforms & Incentives
Professional Development Programs
Commuting Allowance and subsidized parking
Discounted Home, Auto & Pet Insurance
…and more!

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Hard Skills & Tools

clinical researchexternal research strategyfinancial frameworksmilestone paymentsresource utilizationgovernance modelsdata platformsreal-world evidence (RWE)multinational study managementICH GCP guidelines

Soft Skills

leadershipinfluence without authoritynegotiationstrategic mindsetfinancial acumencollaborationproject managementcross-functional teamworkcommunicationprioritization

Certifications

MDPharmDPhD