Global Medical Director, Rare Disease – SMA/ALS, Evidence Generation Lead

Biogen

Global Medical Director leading evidence generation efforts for ALS and SMA portfolios at Biogen. Responsible for registry-based studies, real-world data initiatives, and improving outcomes for patients.

Posted 8/1/2026full-timeCambridge • Massachusetts • 🇺🇸 United StatesSenior💰 $225,000 - $310,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Expertise in leading evidence generation strategies for rare diseases, particularly SMA and ALS, with a strong focus on registry development, statistical analysis, and compliance with industry standards. Proven ability to collaborate with cross-functional teams and engage with external stakeholders to drive impactful research initiatives.

Highest-signal resume keywords

Advanced Degree (MD, PhD, PharmD)Registry Development ExperienceReal-World Data AnalysisProject Leadership SkillsScientific Knowledge of Rare Neuromuscular Diseases

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Evidence Generation StrategyRegistry Protocol DevelopmentStatistical Analysis PlansPublication StrategyDisease Registry DesignNatural History StudiesData AnalysisProject Management

Soft Skills

Strong Communication SkillsRelationship Building

Industry Keywords

Rare DiseasesSMAALSGeneticsBiomarkersPharmaceuticalMedical AffairsClinical Development

About the role

Key responsibilities & impact

Lead the Global Integrated Evidence Generation strategy/plan development for Rare portfolio (SMA and ALS)
Design, prioritize, and oversee evidence generation initiatives
Develop and maintain an integrated evidence generation roadmap across rare portfolio
Collaborate closely with various teams to ensure registry evidence plans are robust and aligned
Lead or contribute to registry protocol development, statistical analysis plans, and publication strategy
Build and nurture relationships with key external stakeholders
Ensure all registry-based evidence generation activities comply with Biogen's standards

Requirements

What you’ll need

Advanced degree (MD, PhD, PharmD, or equivalent) with + 7 years of pharmaceutical, medical affairs, or clinical development experience
Demonstrated, hands-on experience designing, launching, and governing disease registries or natural history studies
Proven track record analyzing registry-derived real-world data
Experience serving on or engaging with registry steering committees, scientific advisory boards, or academic/consortium partnerships
Strong scientific knowledge of rare neuromuscular disease, SMA, ALS, genetics, or biomarkers
Strong communication and project leadership skills

Benefits

Comp & perks

Medical, Dental, Vision, & Life insurances
Fitness & Wellness programs including a fitness reimbursement
Short- and Long-Term Disability insurance
A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
Up to 12 company paid holidays + 3 paid days off for Personal Significance
80 hours of sick time per calendar year
Paid Maternity and Parental Leave benefit
401(k) program participation with company matched contributions
Employee stock purchase plan
Tuition reimbursement of up to $10,000 per calendar year
Employee Resource Groups participation