Senior Principal Biostatistician

Biogen

Senior Principal Biostatistician leading biostatistics for pharmaceutical products requiring advanced study design. Engaging in statistical methodologies and contributing to all stages of clinical research.

Posted 5/21/2026full-timeMassachusetts, North Carolina • 🇺🇸 United StatesSenior💰 $134,000 - $179,000 per yearWebsite

About the role

Key responsibilities & impact

Lead biostatistics representation on project or study teams and provide statistical expertise.
Define statistical methodologies, analyze data, and report results for clinical development plans.
Train and supervise contract statisticians, ensuring quality deliverables.
Assist in addressing statistical issues in regulatory, legal, or other challenges.
Serve as a peer reviewer and internal consultant on broad statistical issues.
Participate in process improvement initiatives and mentor new/junior biostatisticians.
Conduct modeling and simulations as needed.
Collaborate closely with study or project teams for data interpretation and reporting.
Work with statistical programmers, data management, and vendors to deliver analysis results.
Collaborate with medical writers to complete study reports and manuscripts.
Supervise FSP statisticians in assigned tasks.

Requirements

What you’ll need

Degree in Biostatistics (Ph.D Preferred) or equivalent with a minimum of 3+ years relevant work experience in the pharmaceutical/biotech industry.
Thorough understanding of statistical principles and clinical trial methodology.
Ability to provide technical solutions to a wide range of difficult problems.
Conversant with R, SAS, or other statistical software programming languages.
Working knowledge of regulatory guidelines related to statistical analysis.
Strong ability to manage multiple projects and conflicting priorities.
Excellent written and verbal communication skills.

Benefits

Comp & perks

Medical, Dental, Vision, & Life insurances
Fitness & Wellness programs including a fitness reimbursement
Short- and Long-Term Disability insurance
A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
Up to 12 company paid holidays + 3 paid days off for Personal Significance
80 hours of sick time per calendar year
Paid Maternity and Parental Leave benefit
401(k) program participation with company matched contributions
Employee stock purchase plan
Tuition reimbursement of up to $10,000 per calendar year
Employee Resource Groups participation

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

biostatisticsstatistical methodologiesdata analysismodelingsimulationsstatistical principlesclinical trial methodologystatistical software programmingRSAS

Soft Skills

leadershiptrainingsupervisionproblem-solvingproject managementcommunicationmentoringcollaborationpeer reviewprocess improvement

Certifications

Ph.D in Biostatisticsequivalent degree