Director of Commercial Strategy and Operations

BillionToOne

Director of Commercial Strategy and Operations at BillionToOne shaping strategy and operations for the prenatal field team. Collaborate with senior sales leadership to drive commercial success.

Posted 6/17/2026full-timeRemote • 🇺🇸 United StatesLead💰 $246,525 - $267,962 per yearWebsite

About the role

Key responsibilities & impact

Partner with the VP, Commercial Sales–Prenatal to set strategy, annual plans, and the operating cadence (WBRs, MBRs, QBRs) that drives revenue and account expansion
Lead territory design and quarterly rebalancing for a 250-person field team scaling into new geographies, with dotted-line management of the Salesforce admins who power the data
Own incentive compensation design and quarterly quota setting — building plans that reinforce strategic priorities and stand up to finance and field scrutiny
Direct sales analytics, dashboards, and reporting, working closely with the commercial data science team to turn field activity into insight and insight into action
Use data to go from "what" to "why" — and from "why" to "what we should do about it" — synthesizing tangible recommendations from field performance, deal outcomes, competitive signal, and product launches
Treat AI as a force multiplier — building a function that produces several multiples of the analytical output of a traditional sales ops team
Program-manage the highest-priority cross-functional initiatives — acceleration programs, health system adoption, EMR integration — and liaise to bring field signal into Product, Marketing, and Market Access

Requirements

What you’ll need

10+ years across sales strategy, commercial operations, revenue operations, or top-tier management consulting — with material time partnering closely with senior sales leadership
Proven track record designing territories, setting quotas, and building variable comp plans for field sales orgs during rapid growth
Hands-on analytical rigor: you can do data analysis with AI, build a model in Excel, debug a Salesforce report, and present the answer to the VP in the same day
Experience leading high-performing analytical teams, including data scientists or commercial analysts
Excellent communication and executive presence — credible from individual contributor to C-suite
A builder's mindset: high comfort with ambiguity, and the instinct to ship a v1 and iterate.

Benefits

Comp & perks

Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

sales strategycommercial operationsrevenue operationsterritory designquota settingvariable compensation plansdata analysisExcelSalesforceanalytical modeling

Soft Skills

communicationexecutive presenceleadershipanalytical rigorbuilder's mindsetcomfort with ambiguitycollaborationstrategic thinkingproblem-solvingpresentation skills